Description

trans-2-(3-Bromobenzoyl)Cyclopentane-1-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate featuring a brominated aromatic ketone moiety fused to a cyclopentane carboxylic acid structure. This compound is valued for its role as a critical building block in the synthesis of complex, biologically active molecules, particularly in medicinal chemistry and drug discovery. It is primarily sought after by research institutions and pharmaceutical manufacturers developing novel therapeutic agents, where its specific stereochemistry and functional groups are essential for target binding and activity.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new Active Pharmaceutical Ingredients (APIs), especially for central nervous system (CNS) and anti-inflammatory targets.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization processes to modify pharmacokinetic properties.
• Organic Synthesis Building Block: Serves as a versatile precursor for further functionalization, including cross-coupling reactions, reductions, and ring-forming transformations.
• Protease Inhibitor Development: Potential intermediate in the synthesis of compounds targeting specific enzyme families due to its carboxylic acid and ketone functionalities.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and scale-up of novel chemical entities for clinical trials.

Basic Information

Item	Detail
Product Name	trans-2-(3-Bromobenzoyl)Cyclopentane-1-Carboxylic Acid
CAS No.	733740-96-0
Molecular Formula	C13H13BrO3
Molecular Weight	297.15 g/mol
Synonyms	(1R,2S)-2-(3-Bromobenzoyl)cyclopentane-1-carboxylic acid; (1S,2R)-2-(3-Bromobenzoyl)cyclopentane-1-carboxylic acid; trans-2-(3-Bromobenzoyl)cyclopentanecarboxylic acid; 2-(3-Bromobenzoyl)cyclopentane-1-carboxylic Acid; 3-Bromo-trans-2-benzoylcyclopentanecarboxylic Acid; BCPCA; 733740-96-0
EINECS	Contact for details

Quality Control

Our trans-2-(3-Bromobenzoyl)Cyclopentane-1-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency, meeting the stringent requirements for pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting key parameters such as assay, enantiomeric excess, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if specified.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.