Description

1-(1,1-Dioxo-Tetrahydro-1Lambda*6*-Thiophen-3-Yl)-6-Oxo-1,4,5,6-Tetrahydro-Pyridazine-3-Carboxylic A is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure, signifying its role in sophisticated synthetic pathways. Its value lies in enabling the production of novel active pharmaceutical ingredients (APIs) with potential therapeutic benefits, requiring exceptional batch-to-batch consistency and purity. This compound is essential for R&D laboratories and manufacturing facilities in the global pharmaceutical and biotechnology sectors focused on developing new drug candidates.

Application

• Pharmaceutical Intermediate: A critical building block in the multi-step synthesis of novel drug candidates, particularly in medicinal chemistry research.
• API Synthesis: Used in the development and scale-up production of new Active Pharmaceutical Ingredients (APIs), especially those targeting complex disease mechanisms.
• Biochemical Research: Serves as a key reagent or precursor in biochemical assays and pharmacological studies to investigate new biological pathways.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for cGMP-compliant production of clinical trial materials.
• Process Chemistry: Utilized in route scouting and process optimization to develop efficient, scalable, and cost-effective synthetic methodologies.

Basic Information

Product Name	1-(1,1-Dioxo-Tetrahydro-1Lambda*6*-Thiophen-3-Yl)-6-Oxo-1,4,5,6-Tetrahydro-Pyridazine-3-Carboxylic A
CAS No.	732291-88-2
Molecular Formula	C10H11N3O5S
Molecular Weight	285.28 g/mol
Synonyms	1-(1,1-Dioxo-1λ⁶-thiolan-3-yl)-6-oxo-1,4,5,6-tetrahydropyridazine-3-carboxylic acid; 1-(Tetrahydro-1,1-dioxido-3-thienyl)-6-oxo-1,4,5,6-tetrahydropyridazine-3-carboxylic acid; 3-Carboxy-1-(1,1-dioxotetrahydro-3-thienyl)-6-oxo-1,4,5,6-tetrahydropyridazine; 732291-88-2; 1-(1,1-Dioxo-tetrahydro-1λ⁶-thiophen-3-yl)-6-oxo-1,4,5,6-tetrahydro-pyridazine-3-carboxylic acid
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems, ensuring it meets the rigorous standards required for pharmaceutical development. Each batch is subjected to comprehensive analytical testing, including HPLC, NMR, and MS, to verify identity, purity, and impurity profiles. A detailed Certificate of Analysis (COA) is provided with every shipment, and we support customer audits and regulatory submissions with full traceability and documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The container should be kept tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.