Description

2-Bromo-3-(3-Fluorophenyl)-1-Propene is a versatile halogenated aromatic building block of significant interest in advanced organic synthesis. Its molecular architecture, featuring both a reactive bromoalkene handle and a fluorinated phenyl ring, makes it a critical intermediate for constructing complex molecules. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for applications in medicinal chemistry and material science.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the development of new-generation herbicides and fungicides, where the fluorine atom can enhance biological activity and environmental stability.
• Material Science Research: Acts as a monomer or cross-linking agent in the development of specialty polymers and advanced organic frameworks with tailored electronic or optical properties.
• Ligand and Catalyst Development: Employed in the preparation of sophisticated organometallic complexes and chiral ligands for asymmetric catalysis.
• Chemical Biology Probes: Utilized to create fluorescent tags or affinity probes for studying biological pathways and protein interactions.
• Scalable Process Chemistry: Suitable for use in kilo-lab and pilot plant scale-up, supporting route optimization for commercial manufacturing.

Basic Information

Product Name	2-Bromo-3-(3-Fluorophenyl)-1-Propene
CAS No.	731773-05-0
Molecular Formula	C9H8BrF
Molecular Weight	215.06 g/mol
Synonyms	1-Bromo-2-(3-fluorophenyl)ethene; 3-Fluorophenyl vinyl bromide; (3-Fluorophenyl)vinyl bromide; 2-Bromo-1-(3-fluorophenyl)ethene; 1-Bromo-2-(3-fluorophenyl)ethylene; 3-Fluorostyryl bromide; β-Bromo-3-fluorostyrene
EINECS	Contact for details

Quality Control

Every batch of 2-Bromo-3-(3-Fluorophenyl)-1-Propene is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the precise requirements of your research or process development. A detailed Certificate of Analysis (COA) confirming identity, purity, and impurity profiles via techniques such as GC, HPLC, NMR, and MS is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.