Description

2-Bromo-3-(2-Cyanophenyl)Prop-1-Ene is a versatile brominated aromatic building block featuring a reactive alkene and a cyano group. This compound is valued for its role as a key synthetic intermediate in the construction of complex organic molecules, particularly in pharmaceutical and agrochemical research. It is primarily sought after by R&D chemists and process development scientists working in fine chemical synthesis, medicinal chemistry, and material science.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of active pharmaceutical ingredients (APIs) and novel drug candidates, particularly those with complex heterocyclic or substituted aromatic structures.
• Agrochemical Synthesis: Used in the development of advanced pesticides, herbicides, and fungicides, leveraging its reactive sites for molecular diversification.
• Material Science Research: Serves as a monomer or functionalization agent in the development of specialty polymers, liquid crystals, and organic electronic materials.
• Cross-Coupling Reactions: The bromine atom makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck, Sonogashira) to form new carbon-carbon bonds.
• Medicinal Chemistry Library Construction: Employed in high-throughput and combinatorial chemistry to generate diverse compound libraries for biological screening.
• Fine Chemical Production: Used in the multi-step synthesis of complex flavors, fragrances, and dyes.

Basic Information

Product Name	2-Bromo-3-(2-Cyanophenyl)Prop-1-Ene
CAS No.	731772-25-1
Molecular Formula	C10H8BrN
Molecular Weight	222.08 g/mol
Synonyms	2-Bromo-3-(2-cyanophenyl)prop-1-ene; 1-(2-Bromoethenyl)-2-cyanobenzene; 2-(2-Bromovinyl)benzonitrile; (2-Bromovinyl)(o-cyanophenyl)methane; 731772-25-1; 2-Cyanophenyl 2-bromoethene; α-Bromo-2-cyanostyrene
EINECS	Contact for details

Quality Control

Our 2-Bromo-3-(2-Cyanophenyl)Prop-1-Ene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.