Description

5-(2-Methyl-Acryloylamino)-Naphthalene-1-Sulfonyl Chloride is a specialized sulfonyl chloride derivative designed for advanced organic synthesis. This compound is a critical building block for introducing a polymerizable acrylamide moiety linked to a naphthalene sulfonyl group, enabling the creation of functional materials with tailored properties. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced polymer industries for the synthesis of novel active ingredients and specialty monomers.

Application

• Pharmaceutical Intermediate: Key reagent in the synthesis of novel drug candidates, particularly those targeting enzyme inhibition via sulfonamide groups.
• Functional Monomer Synthesis: Serves as a precursor for creating specialty acrylamide monomers used in smart polymers, hydrogels, and responsive materials.
• Fluorescent Probe & Sensor Development: The naphthalene core makes it suitable for constructing fluorescent labeling agents and chemical sensors.
• Agrochemical Research: Used in developing new sulfonamide-based herbicides, fungicides, or plant growth regulators.
• Material Science: Incorporation into polymers for coatings, adhesives, or composites requiring specific chemical functionality and stability.
• Bioconjugation Chemistry: Potential use in modifying biomolecules (proteins, peptides) due to the reactive sulfonyl chloride group.

Basic Information

Product Name	5-(2-Methyl-Acryloylamino)-Naphthalene-1-Sulfonyl Chloride
CAS No.	728864-93-5
Molecular Formula	C₁₄H₁₂ClNO₃S
Molecular Weight	309.77 g/mol
Synonyms	5-[(2-Methyl-1-oxo-2-propen-1-yl)amino]-1-naphthalenesulfonyl chloride; N-(1-Naphthylsulfonyl)methacrylamide chloride; Methacryloyl-1-naphthylamine-5-sulfonyl chloride; 1-Naphthalenesulfonamide, 5-[(2-methyl-1-oxo-2-propen-1-yl)amino]-, chloride; 5-Methacrylamidonaphthalene-1-sulfonyl chloride
EINECS	Contact for details

Quality Control

Every batch of 5-(2-Methyl-Acryloylamino)-Naphthalene-1-Sulfonyl Chloride is manufactured and tested under strict quality management protocols to ensure consistency and reliability for your critical syntheses. Our products undergo rigorous quality testing, including HPLC for purity and identity confirmation via FT-IR and NMR, to ensure compliance with industry standards. Certificates of Analysis (COA) with detailed chromatographic data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.