Description

6(6Ar,10As)-Rel-A,7,8,10A-Tetrahydro-3,6,6,9-Tetramethyl-6H-Dibenzo[B,D]Pyran-1-Ol is a high-purity synthetic cannabinoid derivative of significant interest in advanced pharmaceutical research and development. This compound serves as a critical intermediate or reference standard for the study of cannabinoid receptor pharmacology and the synthesis of novel therapeutic agents. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers engaged in developing next-generation medications targeting neurological and inflammatory pathways.

Application

• Pharmaceutical Intermediate: Key building block in the synthetic pathway for novel cannabinoid-based active pharmaceutical ingredients (APIs).
• Reference Standard: High-purity material for analytical method development, validation, and quality control in cannabinoid research.
• Biochemical Research: Tool compound for in vitro and in vivo studies investigating CB1 and CB2 receptor binding affinity, selectivity, and functional activity.
• Medicinal Chemistry: Core scaffold for structure-activity relationship (SAR) studies aimed at optimizing pharmacokinetic and pharmacodynamic properties.
• Preclinical Development: Used in the synthesis of candidates for preclinical trials targeting pain management, neuroprotection, and anti-inflammatory effects.

Basic Information

Product Name	6(6Ar,10As)-Rel-A,7,8,10A-Tetrahydro-3,6,6,9-Tetramethyl-6H-Dibenzo[B,D]Pyran-1-Ol
CAS No.	728044-69-7
Molecular Formula	C19H26O2
Molecular Weight	286.41 g/mol
Synonyms	1-Hydroxy-3,6,6,9-tetramethyl-6a,7,8,10a-tetrahydro-6H-benzo[c]chromene; (-)-trans-Cannabidiol (CBD) derivative isomer; Rel-6aR,10aR-6,6,9-Trimethyl-3-pentyl-6a,7,8,10a-tetrahydro-6H-benzo[c]chromen-1-ol analog; Dibenzopyranol derivative; Synthetic cannabinoid intermediate; Hexahydrocannabinol (HHC) related compound
EINECS	Contact for details

Quality Control

Our 6(6Ar,10As)-Rel-A,7,8,10A-Tetrahydro-3,6,6,9-Tetramethyl-6H-Dibenzo[B,D]Pyran-1-Ol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC-MS, and NMR, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment supports compliance with cGMP guidelines for pharmaceutical intermediates and research chemicals.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive). For long-term storage, consider using inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.