Description

2H-Pyrido[1,2-a]pyrimidin-2-one, hydrazone (9CI) is a specialized heterocyclic organic compound featuring a fused pyrido-pyrimidinone core with a hydrazone functional group. This unique molecular architecture makes it a valuable advanced pharmaceutical intermediate and a versatile building block in medicinal chemistry research. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for the synthesis of novel bioactive molecules.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential drug candidates targeting various therapeutic areas.
• Medicinal Chemistry Research: Serves as a core scaffold or building block for constructing compound libraries in hit-to-lead and lead optimization programs.
• Agrochemical Development: Used in research for creating new active ingredients for crop protection products.
• Chemical Biology Probes: Utilized in the development of molecular probes to study biological pathways and protein functions.
• Fine Chemical Synthesis: Intermediate for the production of complex, high-value specialty chemicals.
• Academic Research: Employed in university and institutional labs for heterocyclic chemistry studies and novel reaction methodology development.

Basic Information

Item	Details
Product Name	2H-Pyrido[1,2-a]pyrimidin-2-one, hydrazone (9CI)
CAS No.	727352-55-8
Molecular Formula	C8H8N4O
Molecular Weight	176.18 g/mol
Synonyms	2H-Pyrido[1,2-a]pyrimidin-2-one hydrazone; 2-Hydrazinylidene-2H-pyrido[1,2-a]pyrimidin-1-one; 727352-55-8; Pyrido[1,2-a]pyrimidin-2(1H)-one, hydrazone; Hydrazone of 2H-Pyrido[1,2-a]pyrimidin-2-one; 2H-Pyrido[1,2-a]pyrimidin-2-one hydrazone (9CI)
EINECS	Contact for details

Quality Control

Our production of 2H-Pyrido[1,2-a]pyrimidin-2-one, hydrazone adheres to stringent internal quality standards to ensure batch-to-batch consistency and reliability for research and development purposes. Each lot is characterized using advanced analytical techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profile is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place at a controlled room temperature (15-25°C). This compound is easily oxidized and light-sensitive; prolonged exposure to air or light should be avoided to maintain stability and purity.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.