Description

2,3-Dihydrobenzofuran-6-Sulfonyl Chloride is a high-purity, reactive sulfonyl chloride derivative that serves as a critical building block in advanced organic synthesis. This compound is valued for its ability to introduce the sulfonyl functional group, enabling the creation of novel sulfonamides and other pharmacologically active structures. It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of new active pharmaceutical ingredients (APIs) and agrochemicals, where precise molecular construction is paramount.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel sulfonamide-based drug candidates targeting various therapeutic areas.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides with sulfonyl-containing active ingredients.
• Material Science: Employed in the creation of specialty polymers and functional materials where the sulfonyl group modifies physical or chemical properties.
• Chemical Biology Probes: Acts as a reactive handle for labeling proteins or other biomolecules in proteomics and diagnostic assay development.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of complex, bespoke molecules.

Basic Information

Product Name	2,3-Dihydrobenzofuran-6-Sulfonyl Chloride
CAS No.	724446-31-5
Molecular Formula	C8H7ClO3S
Molecular Weight	218.66 g/mol
Synonyms	6-(Chlorosulfonyl)-2,3-dihydrobenzofuran; 2,3-Dihydrobenzofuran-6-sulfonyl chloride; 2,3-Dihydrobenzo[b]furan-6-sulfonyl chloride; 6-Chlorosulfonyl-2,3-dihydrobenzofuran; Dihydrobenzofuransulfonyl chloride; Benzofuran-6-sulfonyl chloride, 2,3-dihydro-
EINECS	Contact for details

Quality Control

Every batch of 2,3-Dihydrobenzofuran-6-Sulfonyl Chloride is manufactured under strict quality management systems. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for sensitive synthetic applications. A detailed Certificate of Analysis (COA) is supplied with each shipment, confirming identity, purity, and impurity profiles as determined by advanced chromatographic and spectroscopic methods.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to prevent decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.