Description

2-(2,4-Difluoro-Phenyl)-Acetamidine is a high-purity organic building block featuring a difluorophenyl moiety linked to an acetamidine group, making it a valuable intermediate for advanced synthesis. This compound is critical for researchers and manufacturers requiring precise molecular architecture in the development of novel active compounds. It is primarily utilized in the pharmaceutical and agrochemical industries for the research and production of new chemical entities, including potential active pharmaceutical ingredients (APIs) and crop protection agents.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel drug candidates, particularly in medicinal chemistry programs targeting various therapeutic areas.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and insecticides, where the fluorine atoms can enhance biological activity and metabolic stability.
• Chemical Research & Development: Serves as a versatile building block in organic synthesis for constructing complex molecules in academic and industrial R&D settings.
• Material Science Precursor: Potential use in the synthesis of specialty chemicals and advanced materials, such as ligands for catalysts or monomers for specialty polymers.
• Bioconjugation & Probe Development: The reactive amidine group makes it suitable for developing biochemical probes and diagnostic agents in life sciences research.

Basic Information

Product Name	2-(2,4-Difluoro-Phenyl)-Acetamidine
CAS No.	723730-74-3
Molecular Formula	C8H8F2N2
Molecular Weight	170.16 g/mol
Synonyms	2-(2,4-Difluorophenyl)acetamidine; 2,4-Difluorophenylacetamidine; Acetamidine, 2-(2,4-difluorophenyl)-; N-(2,4-Difluorophenyl)acetamidine; 723730-74-3; 2-(2,4-Difluoro-phenyl)-acetamidine; α-(2,4-Difluorophenyl)acetamidine
EINECS	Contact for details

Quality Control

Our 2-(2,4-Difluoro-Phenyl)-Acetamidine is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. We employ advanced analytical techniques, including HPLC, GC, and NMR, to verify identity and quantify purity. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment. Our quality system is designed to meet the stringent requirements of cGMP and ISO standards for advanced chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC Area %)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.