Description

2H-Pyran-4-Ol, Tetrahydro-4-Methyl-2-Propyl-, (2R,4R)- (9Ci) is a high-purity, stereochemically defined chiral intermediate of significant interest in advanced organic synthesis. This compound matters for its role as a critical building block in the development of complex, biologically active molecules, offering precise control over molecular architecture. It is primarily needed by research institutions and pharmaceutical companies engaged in the synthesis of novel active pharmaceutical ingredients (APIs), agrochemicals, and specialty fragrances where specific stereochemistry is paramount for function.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel therapeutic agents, particularly in central nervous system (CNS) and anti-infective drug candidates.
• Agrochemical Synthesis: Used in the construction of advanced, stereoselective pesticide and herbicide molecules to enhance efficacy and reduce environmental impact.
• Flavor & Fragrance Ingredient: Serves as a precursor for the synthesis of specific, high-value aroma chemicals where the (2R,4R)- configuration imparts desired olfactory characteristics.
• Asymmetric Catalysis Ligand Precursor: Provides a scaffold for developing novel chiral ligands and organocatalysts used in enantioselective transformations.
• Academic & Industrial Research: A valuable reference standard and starting material in methodological chemistry research focused on stereocontrolled synthesis and natural product total synthesis.

Basic Information

Product Name	2H-Pyran-4-Ol, Tetrahydro-4-Methyl-2-Propyl-, (2R,4R)- (9Ci)
CAS No.	723340-91-8
Molecular Formula	C9H18O2
Molecular Weight	158.24 g/mol
Synonyms	(2R,4R)-4-Methyl-2-propyltetrahydro-2H-pyran-4-ol; (2R,4R)-4-Methyl-2-propyltetrahydropyran-4-ol; 4-Methyl-2-propyltetrahydro-2H-pyran-4-ol, (2R,4R)-; Tetrahydro-4-methyl-2-propyl-2H-pyran-4-ol, (2R,4R)-; (2R,4R)-rel-4-Methyl-2-propyltetrahydro-2H-pyran-4-ol; 723340-91-8; (2R,4R)-4-Methyl-2-propyl-4-hydroxytetrahydropyran
EINECS	Contact for details

Quality Control

Our production of (2R,4R)-4-Methyl-2-propyltetrahydro-2H-pyran-4-ol adheres to stringent quality protocols to ensure batch-to-batch consistency and high enantiomeric purity. Each lot undergoes comprehensive analysis including chiral HPLC for enantiomeric excess (ee) determination, NMR for structural confirmation, and GC for purity assessment. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific customer or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.