Description

4H-Pyran-4-One, 5-Hydroxy-2-[1-Hydroxy-2-[(1-Methylethyl)Amino]Ethyl]- (9Ci) is a specialized organic compound of significant interest in advanced chemical synthesis. This molecule matters as a versatile chiral building block and intermediate, enabling the development of complex pharmacologically active structures. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of new active pharmaceutical ingredients (APIs), particularly for cardiovascular and respiratory applications.

Application

• Pharmaceutical Intermediate: Key chiral synthon in the research and development of β-adrenergic receptor agonists and related therapeutic agents.
• Chemical Research: Serves as a critical building block in organic synthesis for constructing complex heterocyclic frameworks and exploring structure-activity relationships (SAR).
• Asymmetric Synthesis: Used in catalytic and stoichiometric asymmetric reactions to introduce chirality into target molecules.
• Reference Standard: Employed as an analytical standard in quality control laboratories for method development and impurity profiling in pharmaceutical manufacturing.
• Process Chemistry Development: Utilized in scaling up synthetic routes from laboratory to pilot plant scale for new drug candidates.

Basic Information

Product Name	4H-Pyran-4-One, 5-Hydroxy-2-[1-Hydroxy-2-[(1-Methylethyl)Amino]Ethyl]- (9Ci)
CAS No.	721387-09-3
Molecular Formula	C10H17NO4
Molecular Weight	215.25 g/mol
Synonyms	5-Hydroxy-2-[1-hydroxy-2-(isopropylamino)ethyl]-4H-pyran-4-one; 2-[(1R)-1-Hydroxy-2-[(1-methylethyl)amino]ethyl]-5-hydroxy-4H-pyran-4-one; (R)-5-Hydroxy-2-(1-hydroxy-2-(isopropylamino)ethyl)-4H-pyran-4-one; Isoproterenol Pyranone Derivative; A potential intermediate for Levosalbutamol; 4H-Pyran-4-one, 5-hydroxy-2-[1-hydroxy-2-[(1-methylethyl)amino]ethyl]-, (R)-; 721387-09-3
EINECS	Contact for details

Quality Control

Our 4H-Pyran-4-One, 5-Hydroxy-2-[1-Hydroxy-2-[(1-Methylethyl)Amino]Ethyl]- (9Ci) is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing including HPLC for purity and chiral purity, identity confirmation by spectroscopic methods, and control of residual solvents and moisture content. Certificates of Analysis (COA) detailing all test results are provided and available upon request to ensure full traceability and compliance with your research or development protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.