Description

(4-Amino-Tetrahydro-Pyran-4-Yl)-Methanol is a versatile chiral amino alcohol building block of significant interest in advanced organic synthesis. Its unique structure, featuring both amino and hydroxymethyl functional groups on a tetrahydropyran ring, makes it a critical intermediate for constructing complex molecular architectures. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for the synthesis of active pharmaceutical ingredients (APIs) and novel bioactive compounds.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the development of novel APIs, including potential antiviral, antibacterial, and central nervous system (CNS) agents.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, leveraging its chiral center for selective biological activity.
• Ligand and Catalyst Preparation: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Peptidomimetics and Bioisosteres: The tetrahydropyran scaffold is valuable for designing peptide mimics and bioisosteric replacements in medicinal chemistry.
• Fine Chemical Production: Employed in the multi-step synthesis of specialty chemicals and complex natural product analogs.
• Academic and R&D Laboratories: A valuable building block for methodological studies and exploring new chemical space in organic chemistry.

Basic Information

Product Name	(4-Amino-Tetrahydro-Pyran-4-Yl)-Methanol
CAS No.	720706-20-7
Molecular Formula	C6H13NO2
Molecular Weight	131.17 g/mol
Synonyms	4-(Aminomethyl)tetrahydro-2H-pyran-4-ol; 4-(Hydroxymethyl)-4-aminotetrahydropyran; 4-Aminomethyl-4-hydroxytetrahydropyran; 4-Amino-4-(hydroxymethyl)tetrahydropyran; (4-Aminooxan-4-yl)methanol; 4-Piperidinemethanol, 1,2,3,6-tetrahydro-; Tetrahydro-2H-pyran-4-methanol, 4-amino-
EINECS	Contact for details

Quality Control

Our (4-Amino-Tetrahydro-Pyran-4-Yl)-Methanol is produced under strict quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for synthetic applications. A detailed Certificate of Analysis (COA) is provided with each shipment, and we support custom purity requirements for specific R&D or cGMP manufacturing needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.