Description

3-(2-Hydroxyphenyl)-4,5-Dihydroisoxazole-5-Carboxylic Acid (Saltdata: Free) is a high-purity, advanced pharmaceutical intermediate characterized by its specific isoxazoline-carboxylic acid structure. This compound is of significant commercial interest for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily utilized by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing new therapeutic and crop protection agents. Our supply ensures consistent quality and reliable availability for critical R&D and scale-up processes.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and inflammatory pathways.
• Agrochemical Research: Serves as a key scaffold for developing new generation herbicides and fungicides with improved efficacy and environmental profiles.
• Chemical Synthesis: Used as a versatile building block in organic chemistry for constructing complex heterocyclic compounds via its reactive carboxylic acid and isoxazoline functional groups.
• Academic & Industrial R&D: Employed in research laboratories for methodological studies, catalyst development, and exploring new chemical entities.
• Material Science: Potential applications in creating specialty polymers and functional materials due to its aromatic and heterocyclic structure.

Basic Information

Product Name	3-(2-Hydroxyphenyl)-4,5-Dihydroisoxazole-5-Carboxylic Acid (Saltdata: Free)
CAS No.	712347-85-8
Molecular Formula	C10H9NO4
Molecular Weight	207.18 g/mol
Synonyms	5-Isoxazoline-5-carboxylic acid, 3-(2-hydroxyphenyl)-4,5-dihydro-; 3-(2-Hydroxyphenyl)-4,5-dihydro-5-isoxazolecarboxylic acid; 3-(2-Hydroxyphenyl)-δ2-isoxazoline-5-carboxylic acid; 2-(4,5-Dihydroisoxazol-3-yl)phenol-5-carboxylic acid; Isoxazoline carboxylic acid derivative (CAS 712347-85-8); Free acid form of 712347-85-8; 3-(2-Hydroxyphenyl)-4,5-dihydroisoxazol-5-yl)formic acid
EINECS	Contact for details

Quality Control

Our production of 3-(2-Hydroxyphenyl)-4,5-Dihydroisoxazole-5-Carboxylic Acid adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for pharmaceutical intermediate applications. A Certificate of Analysis (COA) detailing all specifications is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids and organic solvents. The container must be kept tightly sealed to protect the contents from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.