Description

Boc-(2S)-Gly-4-Pyranoyl CAS NO 711017-85-5 is a high-purity, protected amino acid derivative specifically engineered for advanced peptide synthesis and pharmaceutical research. This compound serves as a critical chiral building block, enabling the precise construction of complex peptide sequences with defined stereochemistry. It is essential for medicinal chemists and process development scientists in the pharmaceutical, biotechnology, and agrochemical industries who require reliable, high-quality intermediates for drug discovery and development programs.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the solid-phase and solution-phase synthesis of therapeutic peptides and peptidomimetics.
• Drug Discovery & Medicinal Chemistry: Used to introduce specific structural motifs and explore structure-activity relationships (SAR) in novel bioactive compound libraries.
• Bioconjugation & Probe Development: Serves as a precursor for creating labeled peptides or affinity probes used in biochemical assays and diagnostic research.
• Agrochemical Research: Employed in the development of novel peptide-based pesticides and growth regulators.
• Academic & Institutional Research: A valuable reagent for studies in organic synthesis methodology, asymmetric synthesis, and peptide science.

Basic Information

Product Name	Boc-(2S)-Gly-4-Pyranoyl
CAS No.	711017-85-5
Molecular Formula	C₁₃H₂₁NO₆
Molecular Weight	287.31 g/mol
Synonyms	(2S)-2-[(tert-Butoxycarbonyl)amino]-2-(tetrahydro-2H-pyran-4-yl)acetic acid; Boc-Gly(4-THP)-OH; N-(tert-Butoxycarbonyl)-2-(tetrahydro-2H-pyran-4-yl)glycine; Boc-2-(Tetrahydro-2H-pyran-4-yl)glycine; N-Boc-2-(Tetrahydropyran-4-yl)glycine; Boc-Thpg-OH; (S)-2-((tert-Butoxycarbonyl)amino)-2-(tetrahydro-2H-pyran-4-yl)acetic acid
EINECS	Contact for details

Quality Control

Every batch of Boc-(2S)-Gly-4-Pyranoyl is manufactured under strict quality management systems and undergoes comprehensive analytical testing to ensure it meets the high-purity standards required for pharmaceutical R&D. Our quality assurance includes identity confirmation, chiral purity verification, and stringent control of organic impurities. Certificates of Analysis (COA) detailing HPLC purity, chiral HPLC data, and residual solvent levels are provided with each shipment to guarantee traceability and compliance with your project specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The product is sensitive to strong acids and should be kept away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥98.0%
Chiral Purity (Chiral HPLC)	≥99.0% ee
Loss on Drying	≤0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.