Description

Hydroxylamine, o-[(1-Methylethoxy)Carbonyl]- (9Ci) is a specialized organic compound belonging to the class of protected hydroxylamine derivatives. This compound is significant as a versatile synthetic intermediate, offering a reactive hydroxylamine moiety that is stabilized by an isopropoxycarbonyl protecting group. It is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for applications such as the synthesis of heterocycles, oxime formation, and as a building block for more complex active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those requiring hydroxylamine or oxime functional groups.
• Agrochemical Synthesis: Used in the research and development of pesticides and herbicides where its protected amine functionality is crucial.
• Chemical Research & Development: Serves as a versatile reagent in organic synthesis for constructing N-O bonds and introducing protected aminooxy groups into target molecules.
• Material Science Precursor: Potential use in the development of specialty polymers and functional materials that incorporate amine-oxide linkages.
• Bioconjugation Chemistry: Can be utilized for the site-specific modification of proteins or other biomolecules through oxime ligation strategies.

Basic Information

Product Name	Hydroxylamine, o-[(1-Methylethoxy)Carbonyl]- (9Ci)
CAS No.	706748-52-9
Molecular Formula	C5H11NO3
Molecular Weight	133.15 g/mol
Synonyms	O-Isopropoxycarbonylhydroxylamine; Isopropyl Carbonohydroximidic Acid; (Isopropoxycarbonyl)hydroxylamine; Hydroxylamine O-isopropyl carbonate; 1-Methylethyl Carbonohydroximidate; N-Hydroxycarbamic Acid Isopropyl Ester; O-(Isopropyloxycarbonyl)hydroxylamine
EINECS	Contact for details

Quality Control

Our Hydroxylamine, o-[(1-Methylethoxy)Carbonyl]- (9Ci) is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with key parameters including assay (by HPLC or titration), identification (by IR and NMR), and impurity profiles. Our quality commitment aligns with cGMP principles for advanced pharmaceutical intermediates, ensuring reliable performance in your critical synthesis applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). This material is easily oxidized (store under inert atmosphere) and is light-sensitive (store away from light). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert gas such as nitrogen or argon.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.