Description

1-Chloro-3-(Chloromethyl)-5-Fluorobenzene is a versatile halogenated aromatic building block of significant importance in advanced organic synthesis. Its bifunctional structure, featuring both a chloromethyl and a chloro substituent on a fluorobenzene ring, makes it a critical intermediate for constructing complex molecular architectures. This compound is primarily sought after by research and development chemists and process engineers in the pharmaceutical and agrochemical industries for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in the development of fluorinated drug candidates.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides where the fluorine atom enhances biological activity and environmental stability.
• Ligand and Catalyst Preparation: Serves as a precursor for synthesizing specialized ligands and organometallic catalysts used in cross-coupling and other catalytic reactions.
• Material Science Research: Employed in the development of fluorinated polymers, liquid crystals, and other advanced materials with unique electronic or surface properties.
• Custom Synthesis and Contract Manufacturing: A valuable starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	1-Chloro-3-(Chloromethyl)-5-Fluorobenzene
CAS No.	79944-65-3
Molecular Formula	C7H5Cl2F
Molecular Weight	179.02 g/mol
Synonyms	3-(Chloromethyl)-1-chloro-5-fluorobenzene; 5-Fluoro-3-chlorobenzyl Chloride; 1-Chloro-5-fluoro-3-(chloromethyl)benzene; 3-Chloromethyl-5-fluorochlorobenzene; (3-Chloro-5-fluorophenyl)methyl chloride; Benzene, 1-chloro-3-(chloromethyl)-5-fluoro-; α,3-Dichloro-5-fluorotoluene
EINECS	Contact for details

Quality Control

Every batch of 1-Chloro-3-(Chloromethyl)-5-Fluorobenzene is produced and tested under a strict quality management system. Our products undergo rigorous quality testing, including chromatographic purity analysis and identity confirmation, to ensure compliance with industry standards and customer specifications. Certificates of Analysis (COA) documenting batch-specific results are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong acids and incompatible materials. The container should be kept tightly sealed to prevent moisture absorption and maintain product integrity.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.