Description

trans-5-Amino-6-Hydroxy-2,2-Dimethyl-1,3-Dioxacyloheptane is a specialized chiral building block featuring a unique 1,3-dioxane ring fused with an amino-hydroxy functionalized side chain. This compound matters for its role as a key intermediate in the synthesis of complex pharmaceuticals and fine chemicals, where its defined stereochemistry and reactive handles are critical. It is primarily needed by research and development chemists, process development teams, and manufacturers in the pharmaceutical, agrochemical, and advanced material sectors.

Application

• Pharmaceutical Intermediate: A crucial chiral synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in antiviral, antibacterial, and central nervous system (CNS) drug candidates.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides where specific stereochemistry influences biological activity.
• Catalyst and Ligand Preparation: Serves as a precursor for synthesizing chiral ligands and organocatalysts used in asymmetric synthesis.
• Fine Chemical Production: Employed in the manufacture of high-value, complex organic molecules for research and specialty applications.
• Academic and Industrial R&D: A valuable tool for methodological development in organic synthesis and stereochemistry studies.

Basic Information

Product Name	trans-5-Amino-6-Hydroxy-2,2-Dimethyl-1,3-Dioxacyloheptane
CAS No.	79944-37-9
Molecular Formula	C8H15NO4
Molecular Weight	189.21 g/mol
Synonyms	5-Amino-6-hydroxy-2,2-dimethyl-1,3-dioxepane (trans-); (5R,6S)-5-Amino-6-hydroxy-2,2-dimethyl-1,3-dioxepane; (5S,6R)-5-Amino-6-hydroxy-2,2-dimethyl-1,3-dioxepane; trans-5-Amino-6-hydroxy-2,2-dimethyldioxepane; 2,2-Dimethyl-5-amino-6-hydroxy-1,3-dioxepane (trans-); Amino-hydroxy dimethyl dioxepane; Chiral 1,3-dioxepane derivative
EINECS	Contact for details

Quality Control

Our trans-5-Amino-6-Hydroxy-2,2-Dimethyl-1,3-Dioxacyloheptane is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including chiral purity assessment by HPLC, to ensure it meets the high standards required for advanced synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (trans isomer)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.