Description

Kryptofix 22 Dd is a specialized macrocyclic polyether, commonly known as a cryptand, with the CAS registry number 79495-97-9. This compound is a critical reagent in phase-transfer catalysis and complexation chemistry, valued for its ability to selectively bind cations and facilitate reactions in non-polar media. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require precise control over reaction kinetics and selectivity.

Application

• Phase-Transfer Catalysis (PTC): A key catalyst for nucleophilic substitution, alkylation, and polymerization reactions, enabling reactions between reagents in immiscible phases.
• Chemical Synthesis: Used as a complexing agent to solubilize inorganic salts in organic solvents, facilitating a wide range of organic synthesis processes.
• Pharmaceutical Intermediates: Employed in the synthesis of complex drug molecules and active pharmaceutical ingredients (APIs) where selective cation binding is required.
• Polymer Chemistry: Acts as an initiator or catalyst in the production of specialized polymers and resins.
• Analytical Chemistry: Serves as a selective ionophore in the development of chemical sensors and electrodes for cation detection.
• Agrochemical Production: Utilized in the synthesis of certain pesticides and herbicides that require phase-transfer catalytic steps.
• Material Science: Applied in the research and development of novel materials, including liquid crystals and supramolecular assemblies.
• Radiopharmaceuticals: Historically used as a chelating agent in the preparation of certain technetium-99m based diagnostic imaging agents.

Basic Information

Product Name	Kryptofix 22 Dd
CAS No.	79495-97-9
Molecular Formula	C18H36N2O6
Molecular Weight	376.49 g/mol
Synonyms	4,7,13,16,21,24-Hexaoxa-1,10-diazabicyclo[8.8.8]hexacosane; Kryptofix® 222; Kryptofix 222; 1,10-Diaza-4,7,13,16,21,24-hexaoxabicyclo[8.8.8]hexacosane; Cryptand 222; Kryptofix 2.2.2; [2.2.2]Cryptand; 4,7,13,16,21,24-Hexaoxa-1,10-diazabicyclo[8.8.8]hexacos-5-ene
EINECS	Contact for details

Quality Control

Our Kryptofix 22 Dd is produced and tested under a strict quality management system to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality commitment aligns with cGMP principles where applicable, and we support compliance with major pharmacopoeial and industrial standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect product performance. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.