Description

(1-Fluoro-cyclopentyl)-hydroxy-acetonitrile is a versatile fluorinated building block of significant interest in advanced organic synthesis. Its unique structure, featuring both a fluorine atom and a reactive nitrile group on a cyclopentyl scaffold, makes it a critical intermediate for constructing complex molecules. This compound is particularly valuable for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it is used to introduce fluorinated motifs that can dramatically alter a compound's metabolic stability, bioavailability, and binding affinity.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the development of novel active pharmaceutical ingredients (APIs), especially for introducing fluorinated cyclopentyl groups to enhance drug properties.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the fluorine atom can improve biological activity and environmental persistence.
• Material Science Research: Acts as a precursor for specialty polymers and liquid crystals, leveraging the fluorine's influence on material properties like solubility and thermal stability.
• Fluorine Chemistry: A valuable reagent for academic and industrial research focused on developing new fluorination methodologies and exploring structure-activity relationships.
• Custom Synthesis & Contract Manufacturing: Supplied to fine chemical companies engaged in custom synthesis projects requiring specific, high-purity fluorinated intermediates.

Basic Information

Product Name	(1-Fluoro-cyclopentyl)-hydroxy-acetonitrile
CAS No.	79205-55-3
Molecular Formula	C7H10FNO
Molecular Weight	143.16 g/mol
Synonyms	2-(1-Fluorocyclopentyl)-2-hydroxyacetonitrile; Hydroxy(1-fluorocyclopentyl)acetonitrile; 1-Fluorocyclopentaneacetonitrile, α-hydroxy-; (1-Fluorocyclopentyl)(hydroxy)acetonitrile; α-Hydroxy-1-fluorocyclopentaneacetonitrile; 2-Hydroxy-2-(1-fluorocyclopentyl)ethanenitrile
EINECS	Contact for details

Quality Control

Every batch of (1-Fluoro-cyclopentyl)-hydroxy-acetonitrile is produced and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the precise requirements of your synthesis. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is supplied with each shipment, supporting your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic nature, the container should be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation. Recommended long-term storage temperature is 2-8°C.

Specification

Item	Specification
Appearance	White to off-white solid or crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.