Description

9Z,12Z-Octadecadienoic-9,10,12,13-D4 Acid is a high-purity, deuterium-labeled isotopologue of linoleic acid, a key polyunsaturated fatty acid. This stable isotope-labeled compound is essential for advanced analytical research, providing an internal standard for precise quantification and metabolic pathway tracing. It is primarily utilized by researchers and manufacturers in the pharmaceutical, nutritional science, and biochemistry sectors for applications requiring high specificity and accuracy.

Application

• Internal Standard for Mass Spectrometry (MS): Critical for the accurate quantification of linoleic acid and its metabolites in complex biological matrices using GC-MS or LC-MS.
• Metabolic Pathway Tracing: Used in in vitro and in vivo studies to elucidate the metabolism, absorption, and distribution of linoleic acid.
• Pharmaceutical Research & Development: Supports drug discovery and development studies focused on lipid metabolism, inflammation, and related disorders.
• Nutritional Science & Clinical Diagnostics: Enables precise measurement of fatty acid profiles in dietary studies, supplements, and patient samples.
• Biochemical Research: Serves as a labeled precursor or probe in enzymatic studies and lipidomics research.
• Quality Control & Method Validation: Employed in analytical laboratories to validate and ensure the accuracy of fatty acid assay methods.

Basic Information

Product Name	9Z,12Z-Octadecadienoic-9,10,12,13-D4 Acid
CAS No.	79050-23-0
Molecular Formula	C18H28D4O2
Molecular Weight	284.48 g/mol (approx.)
Synonyms	Linoleic-9,10,12,13-d4 Acid; (9Z,12Z)-9,10,12,13-Tetradeuteriooctadeca-9,12-dienoic Acid; 9,10,12,13-Tetradeutero-cis,cis-9,12-Octadecadienoic Acid; Deuterated Linoleic Acid; [9,10,12,13-2H4]-Linoleic Acid; Isotopic Labeled Linoleic Acid; 18:2(n-6) d4
EINECS	Contact for details

Quality Control

Every batch of our deuterium-labeled linoleic acid is manufactured and analyzed under strict quality protocols to ensure isotopic purity and chemical integrity. We provide comprehensive Certificates of Analysis (COA) detailing isotopic enrichment (typically >98 atom % D), chemical purity (by GC or HPLC), and identity confirmation. Our quality system supports research requiring traceable and reliable reference materials.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to minimize oxidation. For long-term storage, keep the sealed container in a freezer. Allow the product to reach room temperature in a desiccator before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	Colorless to pale yellow oil
Identification (IR / NMR)	Conforms to structure
Isotopic Purity (Atom % D)	≥ 98% (by MS)
Chemical Purity (GC / HPLC)	≥ 95%
Solubility	Soluble in organic solvents (ethanol, DMSO, chloroform)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.