Description

(14R*,18R*)-14,18-Dimethyl-1,4,7,10,13-Pentaoxa-16-Azacyclooctadecane is a specialized macrocyclic polyether compound, commonly known as a crown ether derivative, which is valued for its selective ion-binding capabilities. This chemical is a critical tool in advanced chemical synthesis and analytical chemistry, enabling precise control over reaction pathways and separation processes. It is primarily sought by researchers and manufacturers in the pharmaceutical, materials science, and fine chemical sectors for applications requiring specific cation complexation.

Application

• Phase-Transfer Catalyst (PTC): Facilitates reactions between reagents in immiscible phases, enhancing reaction rates and yields in organic synthesis.
• Ionophore for Sensors: Serves as a selective binding agent in the development of ion-selective electrodes (ISEs) and chemical sensors for analytical detection.
• Metal Ion Extraction & Separation: Used in liquid-liquid extraction processes to selectively separate and purify specific metal cations from complex mixtures.
• Pharmaceutical Intermediate: Acts as a building block or templating agent in the synthesis of complex drug molecules and active pharmaceutical ingredients (APIs).
• Polymer Modification: Incorporated into polymer matrices to create ion-conductive materials or to impart specific metal-binding properties.
• Supramolecular Chemistry: A key component in the construction of host-guest complexes and molecular machines for advanced research.

Basic Information

Product Name	(14R*,18R*)-14,18-Dimethyl-1,4,7,10,13-Pentaoxa-16-Azacyclooctadecane
CAS No.	78946-83-5
Molecular Formula	C14H29NO5
Molecular Weight	291.39 g/mol
Synonyms	14,18-Dimethyl-1,4,7,10,13-pentaoxa-16-azacyclooctadecane; Aza-18-crown-6 derivative; Dimethyl-substituted aza-crown ether; 16-Aza-18-crown-6, 14,18-dimethyl-; Nitrogen-containing crown ether; Macrocyclic polyether amine; Ionophore 78946-83-5; Selective cation binder
EINECS	Contact for details

Quality Control

Our (14R*,18R*)-14,18-Dimethyl-1,4,7,10,13-Pentaoxa-16-Azacyclooctadecane is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing key parameters such as assay, identity, and impurity profiles. We support custom synthesis and can tailor specifications to meet specific research or cGMP-grade requirements upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.