Description

tert-Butyldimethylsilyl Glycidyl Ether is a specialized organosilicon compound that serves as a versatile protecting group reagent and synthetic intermediate. Its value lies in its ability to introduce a robust, base-stable silyl protecting group onto hydroxyl functionalities, which is crucial for multi-step organic synthesis. This product is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require precise control over molecular architecture.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of complex drug molecules, particularly for protecting alcohol groups during peptide and nucleoside synthesis.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides where selective protection of functional groups is required.
• Polymer Modification: Acts as a functional monomer or cross-linking agent to introduce epoxy and silyl groups into polymer backbones, enhancing material properties.
• Organic Synthesis Reagent: A critical tool in academic and industrial R&D for constructing complex natural products and fine chemicals via controlled protection/deprotection strategies.
• Surface Chemistry: Employed to functionalize silica and other inorganic surfaces with organic epoxide groups for chromatography or sensor applications.

Basic Information

Product Name	tert-Butyldimethylsilyl Glycidyl Ether
CAS No.	78906-15-7
Molecular Formula	C9H20O2Si
Molecular Weight	188.34 g/mol
Synonyms	Glycidyl tert-Butyldimethylsilyl Ether; TBDMS Glycidyl Ether; [(2,2-Dimethyl-1,1-diphenyl-1-silapropoxy)methyl]oxirane; Oxirane, 2-[(tert-butyldimethylsilyloxy)methyl]-; 2-[(tert-Butyldimethylsilyloxy)methyl]oxirane; tert-Butyl(dimethyl)(glycidyloxy)silane; TBDMS-GE
EINECS	Contact for details

Quality Control

Our tert-Butyldimethylsilyl Glycidyl Ether is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chromatography (GC/HPLC) and spectroscopic methods (NMR, IR), to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided to guarantee compliance with your specific research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from heat, sparks, and open flames.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.