Description

Ethanethioamide, 2,2,2-Trifluoro-N,n-Bis(1-methylethyl)- is a specialized organofluorine and thioamide compound, identified by CAS No. 78904-42-4. This high-purity intermediate is valued for its unique trifluoromethyl and diisopropylamino substituents, which impart specific reactivity and properties critical for advanced synthesis. It is primarily sought by research and development chemists in the pharmaceutical and agrochemical sectors for constructing complex molecules, particularly in medicinal chemistry programs targeting novel bioactive entities.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), especially those incorporating fluorine for enhanced metabolic stability and bioavailability.
• Agrochemical Research: Used in developing novel herbicides, fungicides, and insecticides where the trifluoromethyl group can improve efficacy and environmental profile.
• Advanced Material Synthesis: Serves as a precursor for functionalized ligands or monomers in specialty polymers and advanced materials science.
• Organic Synthesis Reagent: Employed in academic and industrial R&D for constructing complex heterocycles and as a versatile reagent in fluorination and amidation reactions.
• Chemical Biology Probes: Utilized in the development of molecular probes and inhibitors for studying enzyme mechanisms and biological pathways.

Basic Information

Product Name	Ethanethioamide, 2,2,2-Trifluoro-N,n-Bis(1-methylethyl)-
CAS No.	78904-42-4
Molecular Formula	C8H14F3NS
Molecular Weight	213.26 g/mol
Synonyms	2,2,2-Trifluoro-N,N-diisopropylacetothioamide; N,N-Diisopropyl-2,2,2-trifluoroacetothioamide; 2,2,2-Trifluoro-N,N-bis(1-methylethyl)ethanethioamide; Trifluoroacetothioamide diisopropyl; TFAT-DIPA; Acetothioamide, 2,2,2-trifluoro-N,N-diisopropyl-; Ethanethioamide, 2,2,2-trifluoro-N,N-diisopropyl-
EINECS	Contact for details

Quality Control

Our Ethanethioamide, 2,2,2-Trifluoro-N,n-Bis(1-methylethyl)- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and elemental analysis, to ensure high purity and consistent performance. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and oxidizing agents. Due to its fluoride/strong alkali sensitivity, ensure proper segregation in storage areas.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.