Description

6-(4-Bromophenyl)-4-(1H-Indol-3-Yl)-4,5-Dihydro-3(2H)-Pyridazinone is a high-purity, synthetically versatile heterocyclic compound that serves as a critical building block in advanced pharmaceutical research and development. Its unique molecular architecture, featuring fused indole and pyridazinone rings with a bromophenyl substituent, makes it a valuable scaffold for designing novel bioactive molecules. This compound is primarily utilized by medicinal chemists and research organizations in the discovery and synthesis of new therapeutic agents.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Medicinal Chemistry Research: Core scaffold for structure-activity relationship (SAR) studies and library synthesis in high-throughput screening campaigns.
• Biochemical Probe Development: Used to create tool compounds for investigating specific enzyme pathways and protein-protein interactions in biological systems.
• Contract Research & Manufacturing (CRAM): Supplied to CROs and CDMOs for custom synthesis projects and process development for clinical trial materials.
• Academic Research: Employed in university and institutional labs for fundamental studies in organic synthesis and heterocyclic chemistry.

Basic Information

Product Name	6-(4-Bromophenyl)-4-(1H-Indol-3-Yl)-4,5-Dihydro-3(2H)-Pyridazinone
CAS No.	78860-87-4
Molecular Formula	C18H14BrN3O
Molecular Weight	368.23 g/mol
Synonyms	4-(1H-Indol-3-yl)-6-(4-bromophenyl)-4,5-dihydro-3(2H)-pyridazinone; 6-(p-Bromophenyl)-4-(3-indolyl)-4,5-dihydro-3(2H)-pyridazinone; 4,5-Dihydro-6-(4-bromophenyl)-4-(1H-indol-3-yl)-3(2H)-pyridazinone; 78860-87-4; 6-(4-Bromophenyl)-4-(1H-indol-3-yl)-4,5-dihydro-3(2H)-pyridazinone
EINECS	Contact for details

Quality Control

Our 6-(4-Bromophenyl)-4-(1H-Indol-3-Yl)-4,5-Dihydro-3(2H)-Pyridazinone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications and relevant research-grade standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.