Description

(1S,4Ar,8Ar)-2-Hydroxymethyl-5,5,8A-Trimethyl-1,4,4A,5,6,7,8,8A-Octahydro-1-Naphthaleneacetic Acid is a high-purity, functionalized decalin derivative of significant interest in advanced organic synthesis. Its complex, stereochemically defined polycyclic structure makes it a valuable chiral building block and intermediate for pharmaceutical research and fine chemical manufacturing. This compound is primarily sought by R&D chemists and process development scientists in the life sciences sector for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a key chiral precursor in the synthesis of novel therapeutic agents, particularly for steroidal or terpenoid-inspired molecules.
• Advanced Organic Synthesis: Used as a sophisticated building block for constructing complex natural product analogs and fragrances due to its rigid decalin core and functional handles.
• Asymmetric Catalysis Research: Employed as a substrate or ligand precursor in the development of new stereoselective synthetic methodologies.
• Material Science Research: Potential monomer or modifier for creating specialized polymers with unique structural properties derived from its polycyclic framework.
• Reference Standard: Supplied as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	(1S,4Ar,8Ar)-2-Hydroxymethyl-5,5,8A-Trimethyl-1,4,4A,5,6,7,8,8A-Octahydro-1-Naphthaleneacetic Acid
CAS No.	78795-77-4
Molecular Formula	C₁₆H₂₆O₃
Molecular Weight	266.38 g/mol
Synonyms	2-(Hydroxymethyl)-5,5,8a-trimethyl-1,4,4a,5,6,7,8,8a-octahydro-1-naphthaleneacetic acid; (1S,4aR,8aR)-2-(Hydroxymethyl)-5,5,8a-trimethyl-decahydro-1-naphthaleneacetic acid; Decahydro-2-(hydroxymethyl)-5,5,8a-trimethyl-1-naphthaleneacetic acid; (1S,4aR,8aR)-2-Hydroxymethyl-5,5,8a-trimethyl-decahydro-naphthalene-1-acetic acid; Stereoisomer of Podocarpic Acid derivative.
EINECS	Contact for details

Quality Control

Our (1S,4Ar,8Ar)-2-Hydroxymethyl-5,5,8A-Trimethyl-1,4,4A,5,6,7,8,8A-Octahydro-1-Naphthaleneacetic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure high chemical and isomeric purity suitable for research and development applications. Comprehensive Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.