Description

4'-Nitrobenzo-12-Crown-4 is a functionalized crown ether derivative, specifically engineered as a selective ionophore for complexing specific metal cations. This compound matters for its role in facilitating phase-transfer catalysis and enabling precise ion recognition in analytical and synthetic chemistry. It is needed by researchers and manufacturers in the fields of chemical synthesis, sensor development, and materials science for creating advanced separation systems and catalytic processes.

Application

• As a key intermediate in the synthesis of more complex crown ether derivatives and supramolecular structures.
• Utilized in phase-transfer catalysis (PTC) to enhance reaction rates and yields in organic synthesis, particularly for anion activation.
• Functioning as a selective ionophore in the development of ion-selective electrodes (ISEs) and chemical sensors for alkali and alkaline earth metal ions.
• Employed in membrane transport studies and liquid-liquid extraction processes for the separation of specific metal ions.
• Used in academic and industrial R&D for investigating host-guest chemistry and molecular recognition phenomena.
• Potential application in polymer modification to create ion-conductive or sensing materials.

Basic Information

Product Name	4'-Nitrobenzo-12-Crown-4
CAS No.	78554-67-3
Molecular Formula	C14H19NO6
Molecular Weight	297.31 g/mol
Synonyms	Benzo-12-crown-4, 4'-nitro-; 4'-Nitrobenzo-12-crown-4 ether; 4-Nitrobenzo-12-crown-4; 1,4,7,10-Tetraoxacyclododec-2-ylmethyl 4-nitrobenzoate; 4-Nitrobenzoic acid (1,4,7,10-tetraoxacyclododec-2-yl)methyl ester; 2-(Hydroxymethyl)-12-crown-4 4-nitrobenzoate
EINECS	Contact for details

Quality Control

Our 4'-Nitrobenzo-12-Crown-4 is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets high-purity research and industrial standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.