Description

(S)-(-)Hydroxymethyl-3(2H)-Furanone is a high-purity chiral building block and flavor intermediate with significant commercial and research value. Its specific stereochemistry makes it a critical precursor for synthesizing complex molecules in the pharmaceutical and fine chemical industries. This compound is essential for manufacturers and R&D teams developing active pharmaceutical ingredients (APIs), advanced agrochemicals, and high-value flavor and fragrance compounds.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel APIs, particularly in antiviral, anticancer, and neurological drug research.
• Flavor & Fragrance Industry: Serves as a precursor for creating natural-tasting flavor compounds like furaneol and sotolone, used in food, beverage, and perfume formulations.
• Agrochemical Synthesis: Used in the development of advanced, enantiomerically pure pesticides and herbicides for enhanced efficacy and environmental safety.
• Fine Chemical Production: Acts as a versatile building block for synthesizing specialty chemicals, ligands for catalysis, and materials science applications.
• Academic & Industrial Research: A valuable reagent for methodological development in asymmetric synthesis and stereochemistry studies.

Basic Information

Product Name	(S)-(-)Hydroxymethyl-3(2H)-Furanone
CAS No.	78508-96-0
Molecular Formula	C5H6O3
Molecular Weight	114.10 g/mol
Synonyms	(S)-(-)-4-Hydroxymethylbut-2-en-4-olide; (S)-(-)-4-Hydroxymethyl-2-buten-4-olide; (S)-(-)-4-Hydroxymethyl-2-butenolide; (S)-(-)-Tetrahydro-4-hydroxy-2-oxo-2H-furan-3-ylmethanol; (S)-(-)-3-Hydroxymethyl-5H-furan-2-one; (S)-(-)-3-(Hydroxymethyl)dihydrofuran-2(3H)-one; (S)-(-)-HMF; (S)-enantiomer of Furaneol precursor.
EINECS	Contact for details

Quality Control

Our (S)-(-)Hydroxymethyl-3(2H)-Furanone is produced under strict quality management systems to ensure batch-to-batch consistency and high enantiomeric purity. We provide comprehensive analytical documentation, including Certificates of Analysis (COA) with detailed chiral HPLC data, to support regulatory filings and quality assurance protocols for pharmaceutical and food-grade applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Melting Point	Specification available upon request
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.