Description

Ethyl (1S,3R)-3-[(Z)-2-Chloro-2-(4-Chlorophenyl)Ethenyl]-2,2-Dimethyl- Cyclopropane-1-Carboxylate is a high-purity, optically active synthetic intermediate of significant commercial importance. This compound is valued for its role as a key chiral building block in the synthesis of complex organic molecules, particularly in the agrochemical and pharmaceutical sectors. It is primarily sought after by R&D chemists and process development teams for the production of advanced active ingredients.

Application

• Agrochemical Intermediate: A critical precursor in the synthesis of pyrethroid and other advanced insecticide active ingredients.
• Pharmaceutical Synthesis: Serves as a chiral synthon for constructing complex pharmacophores in medicinal chemistry research and development.
• Chemical Research: Used in academic and industrial laboratories for methodological studies in asymmetric synthesis and cyclopropane chemistry.
• Process Chemistry: Employed in scale-up and optimization studies for the commercial manufacturing of specialty chemicals.

Basic Information

Product Name	Ethyl (1S,3R)-3-[(Z)-2-Chloro-2-(4-Chlorophenyl)Ethenyl]-2,2-Dimethyl- Cyclopropane-1-Carboxylate
CAS No.	78479-01-3
Molecular Formula	C16H18Cl2O2
Molecular Weight	313.22 g/mol
Synonyms	(1S,3R)-Ethyl 3-[(Z)-2-Chloro-2-(4-chlorophenyl)ethenyl]-2,2-dimethylcyclopropanecarboxylate; (1S-cis)-3-(2-Chloro-2-(4-chlorophenyl)ethenyl)-2,2-dimethylcyclopropanecarboxylic Acid Ethyl Ester; Ethyl (1S,3R)-3-[(Z)-2-Chloro-2-(4-chlorophenyl)vinyl]-2,2-dimethylcyclopropanecarboxylate; (Z)-(1S,3R)-Ethyl 3-(2-Chloro-2-(4-chlorophenyl)vinyl)-2,2-dimethylcyclopropanecarboxylate; A Chiral Isomer of Ethyl 2,2-Dimethyl-3-(2-chloro-2-(4-chlorophenyl)vinyl)cyclopropanecarboxylate; Pyrethroid Acid Synthon.
EINECS	Contact for details

Quality Control

Our Ethyl (1S,3R)-3-[(Z)-2-Chloro-2-(4-Chlorophenyl)Ethenyl]-2,2-Dimethyl- Cyclopropane-1-Carboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure it meets precise customer specifications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong bases and incompatible materials. For long-term storage, consider holding under an inert atmosphere.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% (1S,3R, Z-isomer)
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.