Description

Decahydroquinoline-5-Carboxylic Acid is a versatile, high-purity bicyclic organic compound that serves as a critical chiral building block and intermediate in advanced chemical synthesis. Its unique fused ring structure and carboxylic acid functionality make it valuable for constructing complex molecular architectures with precise stereochemistry. This compound is essential for research and development in the pharmaceutical and fine chemical industries, particularly for applications requiring rigid, saturated frameworks.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of active pharmaceutical ingredients (APIs), particularly for neurological and cardiovascular targets.
• Asymmetric Catalysis: Used as a precursor or ligand component in the development of novel chiral catalysts for enantioselective reactions.
• Fine Chemical Synthesis: Serves as a building block for creating complex natural product analogs, agrochemicals, and specialty polymers.
• Research & Development: Employed in academic and industrial R&D for method development and exploring new chemical spaces in medicinal chemistry.
• Peptidomimetics: Its constrained structure is valuable for designing and synthesizing peptide mimics to improve metabolic stability and bioavailability.

Basic Information

Product Name	Decahydroquinoline-5-Carboxylic Acid
CAS No.	77823-96-2
Molecular Formula	C10H17NO2
Molecular Weight	183.25 g/mol
Synonyms	5-Carboxydecahydroquinoline; cis/trans-Decahydroquinoline-5-carboxylic Acid; Perhydroquinoline-5-carboxylic Acid; 1,2,3,4,4a,5,6,7,8,8a-Decahydroquinoline-5-carboxylic Acid; 5-Quinolinecarboxylic Acid, decahydro-; DHQ-CA
EINECS	Contact for details

Quality Control

Our Decahydroquinoline-5-Carboxylic Acid is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is subjected to comprehensive analytical testing, including HPLC for assay and chiral purity, and NMR/IR for structural confirmation. A Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed to prevent absorption of atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee (specify isomer)
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.