Description

(2S)-2,3-Dihydro-5,7-Dihydroxy-2-(2-Hydroxyphenyl)-6,8-Dimethyl-4H-1-Benzopyran-4-One CAS NO 77744-53-7 is a chiral, polyphenolic compound belonging to the class of flavanones. This molecule matters for its potential as a key synthetic intermediate or reference standard in the development of bioactive compounds, particularly in pharmaceutical research. It is needed by R&D chemists and process development scientists in the pharmaceutical, nutraceutical, and fine chemical industries for applications in asymmetric synthesis and biological activity studies.

Application

• Pharmaceutical Intermediate: Serves as a chiral building block for the synthesis of novel drug candidates with potential biological activity.
• Reference Standard: Used as a high-purity analytical standard in quality control laboratories for method development and validation.
• Biochemical Research: Employed in academic and industrial research to study structure-activity relationships (SAR) of flavanone derivatives.
• Asymmetric Synthesis: Utilized as a starting material or ligand precursor in catalytic asymmetric reactions due to its defined stereochemistry.
• Nutraceutical Development: Investigated for potential incorporation into advanced dietary supplements or functional food ingredients.
• Organic Synthesis Building Block: Provides a complex, multifunctional core structure for the construction of more elaborate chemical libraries.

Basic Information

Product Name	(2S)-2,3-Dihydro-5,7-Dihydroxy-2-(2-Hydroxyphenyl)-6,8-Dimethyl-4H-1-Benzopyran-4-One
CAS No.	77744-53-7
Molecular Formula	C₁₇H₁₆O₅
Molecular Weight	300.31 g/mol
Synonyms	(2S)-5,7-Dihydroxy-2-(2-hydroxyphenyl)-6,8-dimethylchroman-4-one; (S)-5,7-Dihydroxy-2-(2-hydroxyphenyl)-6,8-dimethyl-4-chromanone; 2,3-Dihydro-5,7-dihydroxy-2-(2-hydroxyphenyl)-6,8-dimethyl-4H-1-benzopyran-4-one, (2S)-; Flavanone derivative 77744-53-7; (S)-6,8-Dimethyl-5,7,2'-trihydroxyflavanone; 2'-Hydroxy-6,8-dimethyl-5,7-dihydroxyflavanone (S-enantiomer); Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our (2S)-2,3-Dihydro-5,7-Dihydroxy-2-(2-Hydroxyphenyl)-6,8-Dimethyl-4H-1-Benzopyran-4-One is produced under a strict quality management system. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, enantiomeric excess, and impurity profiles. Specifications can be aligned with research or cGMP standards as required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is easily oxidized and should be stored under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep the container tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	Off-white to pale yellow powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.2%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.