Description

8-Oxo-5,6,7,8-Tetrahydronaphthalene-1-Carboxylic Acid is a high-purity, functionalized tetralone derivative that serves as a critical advanced pharmaceutical intermediate (API) and versatile organic synthesis building block. Its unique fused-ring structure with a ketone and carboxylic acid group makes it invaluable for constructing complex molecular architectures. This compound is primarily sought by pharmaceutical R&D and fine chemical synthesis teams for developing novel active compounds.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of steroid analogs, tricyclic antidepressants, and other bioactive molecules with a tetralin or tetrahydronaphthalene core.
• Organic Synthesis Building Block: Used in Friedel-Crafts acylation, condensation reactions, and as a starting material for synthesizing complex polycyclic compounds.
• Agrochemical Research: Intermediate for developing novel herbicides and plant growth regulators that leverage its fused aromatic system.
• Material Science: Potential monomer or precursor for specialty polymers and organic electronic materials due to its rigid, planar structure.
• Dye & Pigment Synthesis: Serves as a core structure for developing anthraquinone-like dyes and colorants.
• Academic & Contract Research: Essential reagent for methodological studies in organic chemistry and medicinal chemistry programs.

Basic Information

Product Name	8-Oxo-5,6,7,8-Tetrahydronaphthalene-1-Carboxylic Acid
CAS No.	77635-17-7
Molecular Formula	C11H10O3
Molecular Weight	190.20 g/mol
Synonyms	1-Carboxy-5,6,7,8-tetrahydro-8-oxonaphthalene; 8-Oxo-1,2,3,4-tetrahydronaphthalene-1-carboxylic acid; 5,6,7,8-Tetrahydro-8-oxo-1-naphthoic acid; 8-Oxo-1,2,3,4-tetrahydronaphthalene-1-carboxylic acid; 1-Naphthalenecarboxylic acid, 5,6,7,8-tetrahydro-8-oxo-; Tetralone-1-carboxylic acid; 8-Oxotetralin-1-carboxylic acid
EINECS	Contact for details

Quality Control

Our 8-Oxo-5,6,7,8-Tetrahydronaphthalene-1-Carboxylic Acid is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure high chemical purity and structural identity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, impurity profiles, and physical characteristics. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.