Description

Tetraethylene Glycol p-Toluenesulfonate is a high-purity chemical intermediate featuring a tosylate leaving group on a tetraethylene glycol backbone. This compound matters for its versatility as a key building block in organic synthesis, enabling the controlled introduction of polyether chains into target molecules. It is primarily needed by research and development laboratories, pharmaceutical manufacturers, and specialty chemical producers for applications in polymer chemistry, material science, and the synthesis of complex organic compounds.

Application

• Pharmaceutical Intermediate: Used in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring polyether-linked functional groups or prodrug strategies.
• Polymer & Material Science: Serves as a monomer or chain extender in the production of specialized polyethers, dendrimers, and functional polymers.
• Crosslinking Agent: Employed to create crosslinked networks in resins and polymeric materials, enhancing mechanical properties.
• Surface Modification: Utilized to attach hydrophilic polyether chains to surfaces or molecules, modifying solubility and biocompatibility.
• Ligand & Chelator Synthesis: Acts as a precursor for synthesizing crown ether analogs and other chelating agents for metal ions.
• Organic Synthesis Reagent: Functions as an alkylating agent in nucleophilic substitution reactions to introduce tetraethylene glycol motifs.

Basic Information

Product Name	Tetraethylene Glycol p-Toluenesulfonate
CAS No.	77544-60-6
Molecular Formula	C19H32O7S
Molecular Weight	404.52 g/mol
Synonyms	Tetraethylene glycol tosylate; 2-[2-[2-[2-(4-Methylbenzenesulfonyloxy)ethoxy]ethoxy]ethoxy]ethanol; p-Toluenesulfonic acid tetraethylene glycol ester; Tetraethylene glycol monotosylate; Tetraglycol tosylate; TEG-Ts; TEG-OTs; TetraEG-OTs
EINECS	Contact for details

Quality Control

Our Tetraethylene Glycol p-Toluenesulfonate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong bases and incompatible materials. The product is light-sensitive and should be stored away from light.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.