Description

Chlorotrimethoxybenzene is a versatile aromatic ether derivative characterized by its chlorine and methoxy substituents. This compound serves as a valuable high-purity building block and key intermediate in advanced organic synthesis. It is primarily required by R&D laboratories and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds with complex aromatic backbones.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and other crop protection agents where its substituted benzene ring provides a core structural element.
• Ligand and Catalyst Preparation: Serves as a precursor for synthesizing specialized ligands used in metal-catalyzed coupling reactions and other catalytic processes.
• Material Science Research: Employed in the development of advanced polymers, liquid crystals, and organic electronic materials due to its functionalizable aromatic core.
• Fine Chemical Production: Acts as a starting material for manufacturing dyes, pigments, and other performance chemicals.

Basic Information

Product Name	Chlorotrimethoxybenzene
CAS No.	77241-44-2
Molecular Formula	C9H11ClO3
Molecular Weight	202.63 g/mol
Synonyms	1-Chloro-3,4,5-trimethoxybenzene; 3,4,5-Trimethoxychlorobenzene; Benzene, 1-chloro-3,4,5-trimethoxy-; Chlorotrimethoxybenzene; 3,4,5-Trimethoxy-1-chlorobenzene; 3,4,5-Trimethoxyphenyl chloride; 1-Chloro-3,4,5-trimethoxy-benzene
EINECS	Contact for details

Quality Control

Our Chlorotrimethoxybenzene is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with each shipment, documenting all critical parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible materials such as strong oxidizing agents. The container should be kept tightly sealed in a dry environment to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	64 - 68 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.