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5-[2-Chloro-6-Fluoro-4-(Trifluoromethyl)Phenoxy]-n-Ethylsulfonyl-2-Nit Ro-Benzamide CAS NO 77227-69-1


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CAS No.:77227-69-1

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

5-[2-Chloro-6-Fluoro-4-(Trifluoromethyl)Phenoxy]-n-Ethylsulfonyl-2-Nitrobenzamide is a high-purity, advanced pharmaceutical intermediate designed for the synthesis of complex active ingredients. This compound is critical for research and development in medicinal chemistry, offering a versatile building block with a unique trifluoromethylphenoxy and sulfonamide functional group combination. It is primarily utilized by pharmaceutical manufacturers and R&D laboratories focused on developing novel therapeutic agents, particularly in areas requiring sophisticated halogenated aromatic systems.

Application

  • Pharmaceutical Intermediate: A key precursor in the synthesis of proprietary drug candidates and active pharmaceutical ingredients (APIs).
  • Agrochemical Research: Serves as a building block for developing novel herbicides and pesticides with enhanced activity.
  • Medicinal Chemistry R&D: Used in structure-activity relationship (SAR) studies and lead optimization for new drug discovery programs.
  • Chemical Synthesis: Employed in organic synthesis to introduce specific halogenated and sulfonamide motifs into target molecules.
  • Reference Standard: Used as an analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name 5-[2-Chloro-6-Fluoro-4-(Trifluoromethyl)Phenoxy]-n-Ethylsulfonyl-2-Nitrobenzamide
CAS No. 77227-69-1
Molecular Formula C16H11ClF4N2O6S
Molecular Weight 470.78 g/mol
Synonyms 5-[2-Chloro-6-fluoro-4-(trifluoromethyl)phenoxy]-N-ethylsulfonyl-2-nitrobenzamide; 2-Nitro-5-[2-chloro-6-fluoro-4-(trifluoromethyl)phenoxy]-N-(ethylsulfonyl)benzamide; Benzamide, 5-[2-chloro-6-fluoro-4-(trifluoromethyl)phenoxy]-N-(ethylsulfonyl)-2-nitro-; CAS 77227-69-1
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Quality Control

Our 5-[2-Chloro-6-Fluoro-4-(Trifluoromethyl)Phenoxy]-n-Ethylsulfonyl-2-Nitrobenzamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its light-sensitive and easily oxidized nature, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from heat, sparks, and open flame.

Specification

Item Specification
Appearance Off-white to light yellow crystalline powder
Identification (IR) Conforms to structure
Purity (HPLC) ≥ 98.0%
Loss on Drying ≤ 0.5%
Residue on Ignition ≤ 0.1%
Heavy Metals ≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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