Description

2-Propanone o-(Trimethylsilylmethyl)Oxime is a specialized organosilicon compound, serving as a versatile reagent and synthetic intermediate. Its value lies in the unique reactivity of the oxime and trimethylsilylmethyl functional groups, enabling key transformations in advanced organic synthesis. This product is essential for R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries, where it is used to construct complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for introducing functionalized carbon chains.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, leveraging its reactivity to create novel bioactive molecules.
• Organosilicon Chemistry: Acts as a precursor for silicon-containing compounds used in specialty polymers, coatings, and silicone-based materials.
• Cross-Coupling Reagent: Facilitates palladium-catalyzed and other transition metal-mediated coupling reactions in fine chemical manufacturing.
• Protecting Group Strategy: The oxime functionality can be utilized as a protecting group for carbonyl compounds in multi-step synthetic sequences.
• Academic & Industrial R&D: A valuable tool for methodological development and exploring new reaction pathways in organic chemistry laboratories.

Basic Information

Product Name	2-Propanone o-(Trimethylsilylmethyl)Oxime
CAS No.	77214-53-0
Molecular Formula	C7H17NOSi
Molecular Weight	159.30 g/mol
Synonyms	Acetone O-[(Trimethylsilyl)methyl]oxime; (Trimethylsilylmethyl)acetone oxime; O-(Trimethylsilylmethyl)acetoxime; 2-Propanone, O-[(trimethylsilyl)methyl]oxime; Acetone O-(trimethylsilylmethyl)oxime; TMSM-Acetone Oxime; (Acetone O-(Trimethylsilylmethyl)oxime)
EINECS	Contact for details

Quality Control

Every batch of 2-Propanone o-(Trimethylsilylmethyl)Oxime is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including GC, HPLC, and NMR, to ensure high purity and consistent performance for critical synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); containers must be kept tightly sealed to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.