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2-Propylzinc Bromide Solution 0.5M In T& CAS NO 77047-87-1


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CAS No.:77047-87-1

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

2-Propylzinc Bromide Solution 0.5M In T& CAS NO 77047-87-1 is a versatile organozinc reagent, specifically an alkylzinc halide, widely used in modern organic synthesis. Its primary value lies in enabling highly selective carbon-carbon bond formation, particularly in cross-coupling reactions, which is critical for constructing complex molecular architectures. This product is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries who require reliable, high-purity intermediates for fine chemical synthesis.

Application

  • Negishi Cross-Coupling Reactions: A key reagent for coupling with aryl, vinyl, or alkynyl halides to form new C-C bonds with high selectivity and functional group tolerance.
  • Pharmaceutical Intermediate Synthesis: Used in the scalable production of active pharmaceutical ingredients (APIs) and complex drug candidates.
  • Agrochemical Compound Development: Employed in the synthesis of novel herbicides, fungicides, and plant growth regulators.
  • Advanced Material Precursors: Serves as a building block for creating specialized polymers, liquid crystals, and organic electronic materials.
  • Catalyst and Ligand Preparation: Useful for the synthesis of organometallic catalysts and specialized ligands used in homogeneous catalysis.
  • Asymmetric Synthesis: Can be employed in reactions to introduce chiral propyl groups into target molecules when used with appropriate chiral ligands or auxiliaries.

Basic Information

Item Detail
Product Name 2-Propylzinc Bromide Solution 0.5M In T& CAS NO 77047-87-1
CAS No. 77047-87-1
Molecular Formula C3H7BrZn
Molecular Weight 188.38 g/mol
Synonyms Diisopropylzinc Bromide (common misnomer), Propylzinc Bromide, Isopropylzinc Bromide, Zinc, bromopropyl-; Bromopropylzinc; 1-Bromopropylzinc; (n-Propyl)zinc bromide; Organozinc bromide reagent C3
EINECS Contact for details

Quality Control

Every batch of our 2-Propylzinc Bromide Solution is manufactured and tested under stringent quality protocols to ensure consistency and reliability for critical synthetic applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as concentration, purity, and impurity profiles. Our quality management system is designed to meet the exacting standards required for research and development as well as cGMP-compliant production environments.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (argon or nitrogen) at 2-8°C in a dedicated, well-ventilated area for flammable materials. Due to its pyrophoric and moisture-sensitive nature, the container must be kept sealed and handled using appropriate air-free techniques. The solution is highly volatile and easily oxidized; prolonged exposure to air or moisture must be avoided.

Specification

Item Specification
Appearance Clear, colorless to pale yellow solution
Concentration 0.5 M in Tetrahydrofuran (T&)
Assay (Titration) ≥ 95%
Identity (IR / NMR) Conforms to structure
Water Content (Karl Fischer) < 100 ppm
Metallic Impurities (ICP-MS) Reported on COA

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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