Description

(4Ar,5Ar)-6,7,7Aα,8,10Aα,10B-Hexahydro-5A,10Bβ-Dimethyl-8-Methylene-2H-Furo[3',2':6,7]Oxireno[2,3]Cyclohepta[1,2-B]Pyran-2,9(5Ah)-Dione is a complex, high-purity synthetic intermediate characterized by its intricate fused-ring structure. This compound is valued for its role as a key chiral building block in advanced organic synthesis, particularly for the construction of pharmacologically active molecules. It is primarily sought after by pharmaceutical R&D and fine chemical sectors for developing novel therapeutic agents and complex natural product analogs.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel drug candidates, especially those with complex polycyclic frameworks.
• Advanced Organic Synthesis: Used as a sophisticated chiral synthon for constructing complex natural product analogs and specialty chemicals.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies and lead optimization for new therapeutic targets.
• Process Chemistry Development: Utilized in scaling up synthetic routes for active pharmaceutical ingredients (APIs) requiring this specific stereochemistry.
• Academic & Industrial R&D: A valuable tool for chemists exploring new synthetic methodologies and reaction pathways involving intricate oxygen-containing heterocycles.

Basic Information

Product Name	(4Ar,5Ar)-6,7,7Aα,8,10Aα,10B-Hexahydro-5A,10Bβ-Dimethyl-8-Methylene-2H-Furo[3',2':6,7]Oxireno[2,3]Cyclohepta[1,2-B]Pyran-2,9(5Ah)-Dione
CAS No.	77026-67-6
Molecular Formula	C17H18O5
Molecular Weight	302.32 g/mol
Synonyms	Furo[3',2':6,7]oxireno[2,3]cyclohepta[1,2-b]pyran-2,9-dione, 6,7,7a,8,10a,10b-hexahydro-5a,10b-dimethyl-8-methylene-, (4aR,5aR,10bR)-; 77026-67-6; (4aR,5aR,10bR)-6,7,7a,8,10a,10b-Hexahydro-5a,10b-dimethyl-8-methylenefuro[3',2':6,7]oxireno[2,3]cyclohepta[1,2-b]pyran-2,9-dione; A complex sesquiterpene lactone derivative.
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems. Every batch is characterized and tested using advanced analytical techniques including HPLC, GC, NMR, and chiral analysis to ensure high chemical and isomeric purity. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your regulatory and R&D documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture uptake, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.