Description

14-Deoxy-11,12-Didehydroandrographolide 3,19-Disuccinate CAS NO 76958-99-1 is a chemically modified derivative of andrographolide, a key bioactive diterpenoid lactone from the *Andrographis paniculata* plant. This semi-synthetic compound is engineered to enhance bioavailability and modify the pharmacological profile for advanced research and development applications. It is primarily utilized by pharmaceutical R&D teams, nutraceutical formulators, and academic researchers focused on inflammation, immunology, and metabolic pathways.

Application

• Pharmaceutical Intermediate: Serves as a key building block for the synthesis of novel drug candidates targeting inflammatory and immune-mediated diseases.
• Reference Standard: Used as a high-purity analytical standard in quality control laboratories for the identification and quantification of related compounds in herbal extracts and finished products.
• Biochemical Research: A critical tool for in-vitro and in-vivo studies investigating structure-activity relationships (SAR) of andrographolide derivatives.
• Nutraceutical Development: Employed in the formulation of advanced dietary supplements aimed at modulating immune response and supporting metabolic health.
• Preclinical Studies: Utilized in animal models to evaluate the pharmacokinetics, efficacy, and safety profile of modified andrographolide compounds.

Basic Information

Item	Details
Product Name	14-Deoxy-11,12-Didehydroandrographolide 3,19-Disuccinate
CAS No.	76958-99-1
Molecular Formula	C28H34O10
Molecular Weight	530.57 g/mol
Synonyms	14-Deoxy-11,12-didehydroandrographolide 3,19-disuccinate; Andrographolide 3,19-disuccinate derivative; 14-Deoxy-δ11,12-andrographolide disuccinate; 3,19-Bis(3-carboxypropanoyloxy)-14-deoxy-11,12-didehydroandrographolide; 14-Deoxy-11,12-didehydroandrographolide disuccinate; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our 14-Deoxy-11,12-Didehydroandrographolide 3,19-Disuccinate is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets exacting R&D and reference standard requirements. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.