Description

5-Hexyn-1-Ol, 4-Methylbenzenesulfonate is a specialized organic intermediate featuring both an alkyne and a sulfonate ester functional group, making it a versatile building block for advanced chemical synthesis. This compound is valued for its role in click chemistry and as a protected propargylic alcohol derivative, enabling precise molecular construction. It is primarily utilized by research institutions and industrial R&D departments in the pharmaceutical, agrochemical, and material science sectors for developing novel active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the synthesis of complex drug candidates, particularly those requiring alkyne handles for bioconjugation via Huisgen cycloaddition (click chemistry).
• Agrochemical Research: Used in the development of new pesticides and herbicides, where its reactive alkyne group allows for the creation of novel molecular scaffolds with targeted biological activity.
• Polymer & Material Science: Acts as a functional monomer or cross-linking agent for producing specialty polymers with tailored properties such as thermal stability or specific reactivity.
• Chemical Biology Probes: Employed in the synthesis of molecular probes and tags for labeling biomolecules (proteins, nucleic acids) due to its bio-orthogonal reactivity.
• Liquid Crystal & OLED Precursor: Utilized in the synthesis of advanced organic electronic materials and liquid crystal compounds.
• Organic Synthesis Building Block: Provides a protected propargylic alcohol functionality for multi-step synthetic routes in fine chemical and academic research.

Basic Information

Product Name	5-Hexyn-1-Ol, 4-Methylbenzenesulfonate
CAS No.	76911-01-8
Molecular Formula	C13H16O3S
Molecular Weight	252.33 g/mol
Synonyms	5-Hexyn-1-yl p-toluenesulfonate; 1-Hexyn-5-ol, 4-methylbenzenesulfonate; 5-Hexynyl tosylate; Tosyloxy-5-hexyne; 4-Methylbenzenesulfonic acid 5-hexyn-1-yl ester; 5-Hexyn-1-yl tosylate; p-Toluenesulfonic acid 5-hexyn-1-yl ester; 5-Hexyn-1-ol tosylate
EINECS	Contact for details

Quality Control

Our 5-Hexyn-1-Ol, 4-Methylbenzenesulfonate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.