Description

Destruxin E is a potent cyclic hexadepsipeptide mycotoxin produced by the entomopathogenic fungus *Metarhizium anisopliae*. This compound is of significant interest for its role in insecticidal and immunosuppressive activities, serving as a key tool in biochemical research and agrochemical development. It is primarily utilized by researchers and product developers in the fields of agricultural science, pharmacology, and biotechnology for studying host-pathogen interactions and developing novel biocontrol agents.

Application

• Biochemical Research: A critical reference standard and tool compound for studying the mode of action of fungal toxins, insect immunity, and cellular apoptosis pathways.
• Agrochemical Development: Serves as a model compound for the research and development of novel, environmentally friendly bio-insecticides and pest management solutions.
• Pharmacological Studies: Investigated for its potential immunosuppressive and cytotoxic properties in cell-based assays and biomedical research.
• Entomology & Pathology: Used to study insect-fungal interactions, virulence factors, and the mechanisms of microbial pathogenesis.
• Quality Control & Standardization: Employed as an analytical standard in laboratories for the identification and quantification of destruxin compounds in research samples or commercial formulations.

Basic Information

Product Name	Destruxin E
CAS No.	76689-14-0
Molecular Formula	C30H45N5O8
Molecular Weight	603.71 g/mol
Synonyms	Destruxin E; [1S-[1R*,3S*(1S*,2R*),4S*]]-3-(2-Hydroxy-1-methylpropyl)-1,4-dimethyl-10-oxa-3,13-diazatricyclo[7.3.1.02,7]trideca-2(7),5-diene-8,11-dione; Cyclo[L-Hydroxyisovaleryl-L-N-methylvalyl-(α-hydroxy-β-methylvalyl)-D-leucyl-L-N-methylalanyl-β-alanyl]; A fungal metabolite from Metarhizium anisopliae
EINECS	Contact for details

Quality Control

Our Destruxin E is produced and handled under strict quality protocols to ensure batch-to-batch consistency and high purity for research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity confirmation, and impurity profiles. We adhere to relevant industry standards for high-purity biochemicals to support reliable and reproducible scientific outcomes.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dedicated freezer. Allow the vial to equilibrate to room temperature before opening to minimize moisture condensation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.