Description

n-Isopropylcarbamic Acid 3-(Trimethylsilyl)Propyl Ester is a specialized organosilicon compound featuring a carbamate-protected amine functional group. This unique structure makes it a valuable intermediate in organic synthesis, particularly for the controlled introduction of the isopropylamino moiety. It is primarily sought after by research and development chemists in the pharmaceutical and agrochemical sectors for constructing complex molecules, such as active pharmaceutical ingredients (APIs) and advanced crop protection agents.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, especially those requiring a protected isopropylamine functional group.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides where its specific carbamate structure is integral to the final product's activity.
• Peptide Mimetics & Modifications: Employed in medicinal chemistry for creating peptide analogs and modifying amino acid side chains to enhance stability or bioavailability.
• Material Science Research: Serves as a precursor or surface-modifying agent in the development of specialty silicones and functionalized polymers.
• Cross-Coupling Reactions: Acts as a substrate or reagent in palladium-catalyzed and other metal-mediated coupling reactions to form new carbon-nitrogen or carbon-carbon bonds.

Basic Information

Product Name	n-Isopropylcarbamic Acid 3-(Trimethylsilyl)Propyl Ester
CAS No.	76681-45-3
Molecular Formula	C10H23NO2Si
Molecular Weight	217.38 g/mol
Synonyms	3-(Trimethylsilyl)propyl N-isopropylcarbamate; 1-[[(3-Trimethylsilyl)propoxy]carbonyl]-2-propanamine; N-Isopropyl-3-(trimethylsilyl)propylcarbamate; Isopropylcarbamic Acid 3-(Trimethylsilyl)propyl Ester; (3-Trimethylsilylpropyl) Isopropylcarbamate; 76681-45-3; Carbamic acid, N-(1-methylethyl)-, 3-(trimethylsilyl)propyl ester
EINECS	Contact for details

Quality Control

Our n-Isopropylcarbamic Acid 3-(Trimethylsilyl)Propyl Ester is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including chromatography (HPLC, GC) and spectroscopic methods (NMR, IR), to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support cGMP compliance for pharmaceutical applications and can tailor purity grades to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC/GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.