Description

6-Methyl-1-Cyclohexenyl Triflate is a specialized organotriflate reagent, a key building block in advanced organic synthesis. Its primary value lies in its role as a versatile electrophile for introducing the 6-methyl-1-cyclohexenyl moiety via cross-coupling reactions, enabling the construction of complex molecular architectures. This high-purity intermediate is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-quality reagents for complex synthetic routes.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for steroidal or complex alicyclic compounds.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and insecticides that require specific cyclohexenyl structural motifs.
• Cross-Coupling Reactions: Serves as an effective electrophilic partner in palladium-catalyzed reactions such as Suzuki-Miyaura, Negishi, and Stille couplings.
• Material Science Research: Employed in the creation of specialized monomers or ligands for catalysts and functional polymers.
• Academic & R&D Laboratories: A valuable tool for methodological development and exploring new synthetic pathways in organic chemistry.
• Fine Chemical Production: Used in the multi-step synthesis of high-value, low-volume specialty chemicals and flavors/fragrances intermediates.

Basic Information

Product Name	6-Methyl-1-Cyclohexenyl Triflate
CAS No.	76605-82-8
Molecular Formula	C8H13F3O3S
Molecular Weight	246.25 g/mol
Synonyms	1-Cyclohexene-1-methanol, 6-methyl-, 1-trifluoromethanesulfonate; 6-Methylcyclohex-1-en-1-yl trifluoromethanesulfonate; 6-Methyl-1-cyclohexenyl trifluoromethanesulfonate; Trifluoromethanesulfonic acid 6-methyl-1-cyclohexen-1-yl ester; 6-Methyl-1-cyclohexenyl triflate; 6-Methylcyclohex-1-enyl Triflate
EINECS	Contact for details

Quality Control

Every batch of 6-Methyl-1-Cyclohexenyl Triflate is manufactured under strict quality management systems and undergoes rigorous analytical testing to ensure consistency and high purity. Our standard quality commitment includes comprehensive analysis via NMR, HPLC, and GC to verify identity, purity, and impurity profiles. Certificates of Analysis (COA) documenting all critical quality attributes are available upon request and can be tailored to meet specific customer or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.