Description

1,2-o-Isopropylidene-β-D-Fructofuranose is a protected sugar derivative, a key chiral intermediate in organic synthesis. Its primary value lies in providing a stable, non-reducing fructose scaffold for the controlled construction of complex carbohydrate molecules and other fine chemicals. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries, where precise stereochemistry is critical for developing active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block for the synthesis of nucleoside analogs, antiviral drugs, and other active pharmaceutical ingredients (APIs) requiring specific sugar moieties.
• Glycochemistry Research: Used as a protected starting material for the preparation of complex oligosaccharides, glycoconjugates, and glycomimetics in academic and industrial R&D.
• Agrochemical Synthesis: Acts as a chiral precursor in the production of certain herbicides, fungicides, and plant growth regulators.
• Fine Chemical Production: Employed in the manufacture of specialty surfactants, ligands for catalysis, and other value-added chemicals derived from carbohydrate chemistry.
• Flavor and Fragrance Industry: Potential intermediate for synthesizing specific sweeteners or aroma compounds with natural sugar backbones.

Basic Information

Product Name	1,2-o-Isopropylidene-β-D-Fructofuranose
CAS No.	76549-76-3
Molecular Formula	C9H16O6
Molecular Weight	220.22 g/mol
Synonyms	1,2-O-Isopropylidene-β-D-fructofuranose; 1,2:4,5-Di-O-isopropylidene-β-D-fructopyranose (common misnomer); D-Fructose 1,2-O-isopropylidene acetal; Isopropylidene fructose; 1,2-O-(1-Methylethylidene)-β-D-fructofuranose; 76549-76-3; β-D-Fructofuranose, 1,2-O-(1-methylethylidene)-
EINECS	Contact for details

Quality Control

Our 1,2-o-Isopropylidene-β-D-Fructofuranose is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identification by IR and NMR spectroscopy, to ensure it meets the high standards required for synthetic applications. Certificates of Analysis (COA) with detailed specifications are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Optical Rotation [α]²⁰D	-80° to -85° (c=1 in H₂O)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.