Description

4-Penten-1-One, 1-(4-Bromophenyl)- is a specialized organic building block featuring a reactive α,β-unsaturated ketone moiety and a bromophenyl substituent. This unique structure makes it a valuable intermediate for synthesizing more complex molecules in pharmaceutical and advanced material research. It is primarily sought after by R&D chemists and process development scientists working in medicinal chemistry and fine chemical synthesis.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring functionalized aryl ketone scaffolds.
• Medicinal Chemistry Research: Used in hit-to-lead optimization and library synthesis for drug discovery programs targeting various therapeutic areas.
• Fine Chemical Synthesis: Acts as a versatile building block for constructing complex organic molecules, including natural product analogs and specialty chemicals.
• Material Science Precursor: Potential use in the development of organic electronic materials or functional polymers due to its conjugated system and halogen atom.
• Cross-Coupling Reactions: The bromine atom makes it a suitable substrate for palladium-catalyzed reactions like Suzuki or Heck couplings to form biaryl structures.
• Chemical Biology Probes: Can be utilized to develop molecular probes or tags for studying biological systems.

Basic Information

Product Name	4-Penten-1-One, 1-(4-Bromophenyl)-
CAS No.	76173-08-5
Molecular Formula	C11H11BrO
Molecular Weight	239.11 g/mol
Synonyms	1-(4-Bromophenyl)-4-penten-1-one; 4'-Bromobenzalacetone; (4-Bromophenyl)vinyl ketone; 4-Penten-1-one, 1-(4-bromophenyl)-; p-Bromobenzylideneacetone; 4-Bromochalcone (precursor); 1-(4-Bromophenyl)pent-4-en-1-one
EINECS	Contact for details

Quality Control

Our 4-Penten-1-One, 1-(4-Bromophenyl)- is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flames. Due to its light-sensitive nature, containers should be amber-colored or stored in dark conditions.

Specification

Item	Specification
Appearance	Off-white to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.