Description

4'-Chloro-5-Fluoro-3-Biphenylacetic Acid is a high-purity, multi-functional biphenyl derivative that serves as a critical building block in advanced organic synthesis. Its unique halogenated structure makes it an invaluable intermediate for creating complex molecules with targeted biological or material properties. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and advanced materials sectors seeking to develop new active ingredients and functional compounds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel non-steroidal anti-inflammatory drugs (NSAIDs) and other bioactive molecules.
• Agrochemical Synthesis: Used in the research and development of new-generation herbicides and fungicides, leveraging its halogenated biphenyl core.
• Material Science Research: Serves as a monomer or functional additive in the development of specialty polymers and liquid crystals.
• Chemical Research: A versatile scaffold for medicinal chemistry, enabling structure-activity relationship (SAR) studies and library synthesis.
• Fine Chemical Production: Employed in custom synthesis and contract manufacturing for high-value, low-volume specialty chemicals.

Basic Information

Product Name	4'-Chloro-5-Fluoro-3-Biphenylacetic Acid
CAS No.	75852-62-9
Molecular Formula	C14H10ClFO2
Molecular Weight	264.68 g/mol
Synonyms	3-Biphenylacetic acid, 4'-chloro-5-fluoro-; 2-(4'-Chloro-5-fluoro[1,1'-biphenyl]-3-yl)acetic acid; 4'-Chloro-5-fluoro-3-phenylphenylacetic acid; 5-Fluoro-4'-chloro-3-biphenylacetic acid; [1,1'-Biphenyl]-3-acetic acid, 4'-chloro-5-fluoro-; 4'-Chloro-5-fluoro-[1,1'-biphenyl]-3-yl-acetic acid
EINECS	Contact for details

Quality Control

Our 4'-Chloro-5-Fluoro-3-Biphenylacetic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the stringent requirements of our global clientele. Certificates of Analysis (COA) with full traceability are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.