Description

(1R,4S,7-Syn)-7-Chloro-1-Methylbicyclo[2.2.1]Heptan-2-One is a high-purity, stereochemically defined bicyclic ketone that serves as a critical chiral building block in advanced organic synthesis. Its unique, rigid molecular framework and specific stereochemistry make it an invaluable intermediate for constructing complex, biologically active molecules. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries seeking to develop novel active ingredients with precise three-dimensional structures.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and antiviral research.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides where specific stereochemistry is crucial for biological activity.
• Asymmetric Catalysis Research: Serves as a model substrate or a ligand precursor in the development of new stereoselective catalytic reactions.
• Fragrance & Flavor Chemistry: Potential intermediate for creating complex, stereochemically pure odorants and flavor molecules with unique organoleptic properties.
• Material Science Research: Building block for synthesizing specialty polymers or liquid crystals with specific structural motifs derived from its rigid bicyclic core.
• Academic & Process Chemistry: A valuable compound for methodological studies in organic synthesis and for scaling up synthetic routes to complex targets.

Basic Information

Product Name	(1R,4S,7-Syn)-7-Chloro-1-Methylbicyclo[2.2.1]Heptan-2-One
CAS No.	75819-72-6
Molecular Formula	C8H11ClO
Molecular Weight	158.62 g/mol
Synonyms	7-Chloro-1-methylbicyclo[2.2.1]heptan-2-one (endo, syn isomer); (1R,4S,7R)-7-Chloro-1-methylbicyclo[2.2.1]heptan-2-one; endo-7-Chloro-1-methylnorbornan-2-one; 7-Chloro-1-methyl-2-norbornanone; Bicyclo[2.2.1]heptan-2-one, 7-chloro-1-methyl-, (1R,4S,7R)-; Chiral norbornane derivative; 75819-72-6
EINECS	Contact for details

Quality Control

Our (1R,4S,7-Syn)-7-Chloro-1-Methylbicyclo[2.2.1]Heptan-2-One is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high chemical purity. We employ advanced analytical techniques including chiral HPLC, GC-MS, and NMR to verify identity, stereochemical purity, and impurity profiles. Certificates of Analysis (COA) detailing all specifications are provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong bases and incompatible organic solvents. The container should be kept tightly sealed to prevent moisture absorption and potential degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.