Description

(1R,4S,7-Anti)-7-Chloro-1-Methylbicyclo[2.2.1]Heptan-2-One is a high-purity, stereochemically defined bicyclic ketone intermediate of significant interest in advanced organic synthesis. Its rigid, functionalized norbornane-like structure makes it a valuable chiral building block for the development of complex molecules. This compound is primarily sought by R&D and process chemistry teams in the pharmaceutical and agrochemical industries for applications in asymmetric synthesis and medicinal chemistry.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel active pharmaceutical ingredients (APIs), particularly in programs targeting central nervous system (CNS) or anti-infective agents.
• Agrochemical Synthesis: Used in the synthesis of advanced, stereospecific pesticide and herbicide candidates, leveraging its unique bicyclic framework.
• Asymmetric Catalysis Research: Serves as a sophisticated substrate or ligand precursor in the development and testing of new chiral catalysts and methodologies.
• Fine Chemical Production: Employed in the multi-step synthesis of specialty chemicals, flavors, and fragrances requiring high stereochemical purity.
• Academic & Institutional Research: A valuable compound for university and institutional labs studying reaction mechanisms, stereochemistry, and the synthesis of complex natural product analogs.

Basic Information

Product Name	(1R,4S,7-Anti)-7-Chloro-1-Methylbicyclo[2.2.1]Heptan-2-One
CAS No.	75819-71-5
Molecular Formula	C8H11ClO
Molecular Weight	158.62 g/mol
Synonyms	7-Chloro-1-methylbicyclo[2.2.1]heptan-2-one (endo, anti isomer); (1R,4S,7R)-7-Chloro-1-methylbicyclo[2.2.1]heptan-2-one; endo-7-Chloro-1-methylnorbornan-2-one; 7-Chloro-1-methyl-2-norbornanone; anti-7-Chloro-1-methylbicyclo[2.2.1]heptan-2-one; Chiral norbornane ketone derivative; Bicyclo[2.2.1]heptan-2-one, 7-chloro-1-methyl-, (1R,4S,7R)-
EINECS	Contact for details

Quality Control

Every batch of (1R,4S,7-Anti)-7-Chloro-1-Methylbicyclo[2.2.1]Heptan-2-One is manufactured under strict quality management systems. We provide comprehensive analytical data to ensure identity, purity, and stereochemical integrity, meeting the stringent requirements of research and process development. Certificates of Analysis (COA) with detailed chromatographic and spectroscopic data (including chiral purity) are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). Keep away from strong bases and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% de
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.