Description

Ethanone, 1-Cyclopropyl-2,2,2-Trifluoro- (9Ci) is a specialized trifluoromethyl ketone derivative, a high-value building block in advanced organic synthesis. Its unique structure, featuring a cyclopropyl ring adjacent to a trifluoroacetyl group, makes it a critical intermediate for introducing fluorinated motifs into target molecules, which can dramatically alter their physical, chemical, and biological properties. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries seeking to optimize the potency, metabolic stability, and bioavailability of new active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the development of novel active pharmaceutical ingredients (APIs), particularly for introducing the metabolically stable trifluoromethyl group.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where fluorination enhances lipophilicity and biological activity.
• Material Science Research: Acts as a precursor for synthesizing fluorinated polymers, liquid crystals, or organic electronic materials with unique properties.
• Medicinal Chemistry: A valuable scaffold in drug discovery programs for creating compound libraries and probing structure-activity relationships (SAR).
• Chemical Synthesis: Employed in various fluorination reactions and as a building block for complex natural product analogs and specialty chemicals.

Basic Information

Product Name	Ethanone, 1-Cyclopropyl-2,2,2-Trifluoro- (9Ci)
CAS No.	75702-97-5
Molecular Formula	C5H5F3O
Molecular Weight	138.09 g/mol
Synonyms	1-Cyclopropyl-2,2,2-trifluoroethanone; 2,2,2-Trifluoro-1-cyclopropylethanone; Cyclopropyl trifluoromethyl ketone; Trifluoroacetylcyclopropane; 1-Cyclopropyl-2,2,2-trifluoroacetone; α,α,α-Trifluoroacetylcyclopropane; (Cyclopropyl)trifluoromethyl ketone
EINECS	Contact for details

Quality Control

Our Ethanone, 1-Cyclopropyl-2,2,2-Trifluoro- (9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.