Description

Methyl 3-Hydrazinothiophene-2-Carboxylate is a specialized heterocyclic building block featuring both a hydrazine and a carboxylate ester functional group on a thiophene core. This unique structure makes it a valuable intermediate for synthesizing complex molecules, particularly in pharmaceutical research and fine chemical manufacturing. It is primarily sought by R&D chemists and process development scientists in the agrochemical and pharmaceutical industries for constructing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and anti-infective agents.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and insecticides, leveraging the thiophene scaffold for bioactivity.
• Material Science Research: Serves as a monomer or functionalizing agent in the creation of advanced polymers and conductive materials.
• Chemical Biology & Proteomics: Employed as a reactive handle for bioconjugation and the development of chemical probes due to its hydrazine moiety.
• Academic & Industrial R&D: A versatile building block for method development and exploring new heterocyclic chemistry in organic synthesis.

Basic Information

Product Name	Methyl 3-Hydrazinothiophene-2-Carboxylate
CAS No.	75681-13-9
Molecular Formula	C6H8N2O2S
Molecular Weight	172.21 g/mol
Synonyms	3-Hydrazinylthiophene-2-carboxylic acid methyl ester; Methyl 3-hydrazinyl-2-thiophenecarboxylate; 2-Thiophenecarboxylic acid, 3-hydrazinyl-, methyl ester; 3-Hydrazinothiophene-2-carboxylic acid methyl ester
EINECS	Contact for details

Quality Control

Our production of Methyl 3-Hydrazinothiophene-2-Carboxylate adheres to stringent quality management protocols. Every batch is characterized and tested to ensure identity, purity, and consistency, meeting the exacting standards required for research and commercial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity (typically >97% by HPLC), physical characteristics, and spectroscopic data (NMR, IR, MS) is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to store under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.