Description

Butyl Triflate is a highly reactive organotriflate ester, widely recognized as a powerful alkylating and butylating agent in advanced organic synthesis. Its value lies in its exceptional ability to introduce the butyl group under mild conditions, facilitating efficient carbon-carbon and carbon-heteroatom bond formation. This reagent is essential for researchers and process chemists in the pharmaceutical, agrochemical, and specialty chemical industries, where it is used to construct complex molecular architectures, develop active pharmaceutical ingredients (APIs), and create novel materials.

Application

• Pharmaceutical Intermediate Synthesis: A key reagent for the alkylation of nitrogen, oxygen, and carbon nucleophiles in the production of active pharmaceutical ingredients (APIs) and drug candidates.
• Agrochemical Manufacturing: Used in the synthesis of herbicides, fungicides, and insecticides by introducing the butyl moiety into target molecules.
• Polymer & Material Science: Serves as a monomer or initiator in the development of specialized polymers, coatings, and advanced functional materials.
• Fine Chemical Production: Employed in multi-step organic synthesis for creating complex natural products, flavors, fragrances, and dyes.
• Catalysis & Ligand Synthesis: Useful for preparing butylated phosphines, amines, and other ligands used in transition metal catalysis.
• Laboratory Research & Development: A staple reagent in academic and industrial R&D labs for methodological development and exploratory synthesis.

Basic Information

Product Name	Butyl Triflate
CAS No.	75618-25-6
Molecular Formula	C5H9F3O3S
Molecular Weight	206.18 g/mol
Synonyms	Butyl Trifluoromethanesulfonate; n-Butyl Triflate; Trifluoromethanesulfonic Acid Butyl Ester; 1-Butyl Triflate; Butyl Trifluoromethanesulphonate; n-Butyl Trifluoromethanesulphonate; Butyl Triflate Reagent; Butyl Ester of Triflic Acid
EINECS	Contact for details

Quality Control

Our Butyl Triflate is manufactured under strict quality control protocols to ensure high purity and batch-to-batch consistency, suitable for demanding synthetic applications. Each lot is analyzed using advanced techniques including NMR, HPLC, and GC to verify identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We adhere to cGMP principles where applicable to support our customers in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a recommended temperature of 2°C to 8°C (refrigerated). Due to its hygroscopic and moisture-sensitive nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent decomposition. Keep away from heat, sparks, open flames, and incompatible materials such as strong bases and nucleophiles.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Acidity (Titration)	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.